5-(tert-Butyldimethylsilyloxy)-1-pentanol
5-(tert-Butyldimethylsilyloxy)-1-pentanol (CAS: 83067-20-3) is an organic compound with a molecular weight of 218.41 g/mol. This silyl-protected alcohol serves as a valuable building block in organic synthesis. Its structure features a primary alcohol functional group protected by a tert-butyldimethylsilyl (TBDMS) ether, making it useful for selective reactions and multi-step syntheses in the pharmaceutical and fine chemical industries.
Organic Synthesis Intermediate
This compound functions as a versatile intermediate in the construction of complex organic molecules. The TBDMS protecting group allows for selective functionalisation of other parts of a molecule before deprotection of the primary alcohol.
Pharmaceutical Building Block
It is utilised in the synthesis of active pharmaceutical ingredients (APIs) and related compounds. The protected alcohol can be incorporated into drug scaffolds or used in the development of novel therapeutic agents.
Fine Chemical Manufacturing
Employed in the production of various fine chemicals requiring specific functional group manipulation. Its predictable reactivity makes it suitable for precise chemical transformations.
| Molecular weight | 218.41 |
|---|---|
| Linear formula | (CH3)3CSi(CH3)2O(CH2)5OH |
| Assay | 90% |
| Boiling point | 140 °C/6 mmHg(lit.) |
| Density | 0.885 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.442(lit.) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(tert-Butyldimethylsilyloxy)-1-pentanol used for?
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5-(tert-Butyldimethylsilyloxy)-1-pentanol is primarily used as a building block and intermediate in organic synthesis, particularly in the pharmaceutical and fine chemical industries, due to its protected primary alcohol functionality.
What are the CAS number and chemical formula for this compound?
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The CAS number for 5-(tert-Butyldimethylsilyloxy)-1-pentanol is 83067-20-3. Its linear formula is (CH3)3Si(CH3)2O(CH2)5OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(tert-Butyldimethylsilyloxy)-1-pentanol at a minimum assay of 90%. This product is intended for research and general chemical use; it is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-(tert-Butyldimethylsilyloxy)-1-pentanol be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. This compound is combustible with a flash point above 113 °C (235.4 °F) and should be kept away from heat and open flames. Consult the Safety Data Sheet for full details.
How is 5-(tert-Butyldimethylsilyloxy)-1-pentanol typically packed and shipped?
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Products are packed securely in appropriate containers for safe transit and are exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation, please contact our sales department through the provided channels on our website, referencing the product name and CAS number.
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