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Methyl 3-chloro-3-oxopropionate

CAS 37517-81-0CH3OCOCH2COClChemical Synthesis

Methyl 3-chloro-3-oxopropionate (CAS 37517-81-0), molecular formula CH3OCOCH2COCl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
Methyl chloroformylacetate,Methyl malonyl chloride
Methyl 3-chloro-3-oxopropionate
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks
01 /Properties
Molecular weight136.53
Linear formulaCH3OCOCH2COCl
Assay97%
Boiling point57-59 °C/12 mmHg(lit.)
Density1.273 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.432(lit.)
Storage temperature2-8°C
ApplicationMethyl 3-chloro-3-oxopropionate was used as a reagent in the synthesis of resin-bound 4-tosyl quinolinone1, 1-anthracen-9-ylmethyl 3-methyl 2,2-dimethylmalonate and 1-(4-(3,5-dihydropyren-1-yl)butyl)-3-methyl 2,2-dimethylmalonate2.
02 /Safety & handling
Corrosive
Corrosive
Harmful / irritant
Harmful / irritant
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point80 °C / 176 °F
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34-36/37
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
37517-81-0
MDL number
MFCD00013657
PubChem substance
24850046
Beilstein registry
1754078
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Methyl 3-chloro-3-oxopropionate?

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Methyl 3-chloro-3-oxopropionate (CAS 37517-81-0), molecular formula CH3OCOCH2COCl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of Methyl 3-chloro-3-oxopropionate does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Methyl 3-chloro-3-oxopropionate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of Methyl 3-chloro-3-oxopropionate?

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Methyl 3-chloro-3-oxopropionate has CAS number 37517-81-0 and molecular formula CH3OCOCH2COCl. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for Methyl 3-chloro-3-oxopropionate?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of Methyl 3-chloro-3-oxopropionate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should Methyl 3-chloro-3-oxopropionate be stored?

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Store Methyl 3-chloro-3-oxopropionate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is Methyl 3-chloro-3-oxopropionate used for?

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Methyl 3-chloro-3-oxopropionate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for Methyl 3-chloro-3-oxopropionate?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need Methyl 3-chloro-3-oxopropionate in a specific grade or volume?

Request a quote