Methyl 3-chloro-3-oxopropionate
Methyl 3-chloro-3-oxopropionate (CAS 37517-81-0) is a valuable organic building block and carbonyl compound with the linear formula CH3OCOCH2COCl and a molecular weight of 136.53 g/mol. This acid halide serves as a key reagent in organic synthesis, particularly for creating complex molecules. It is supplied by Tech Serve Solutions with a purity of 97%, making it suitable for various research and development applications.
- IUPAC
- Methyl chloroformylacetate,Methyl malonyl chloride
- Synonyms
- Methyl malonyl chlorideMethyl chloroformylacetate
Synthesis of Resin-Bound Quinolinones
Methyl 3-chloro-3-oxopropionate is utilised as a reagent in the synthetic pathway towards resin-bound 4-tosyl quinolinone derivatives, contributing to the development of novel chemical structures.
Intermediate for Complex Malonates
This compound facilitates the synthesis of complex malonate esters, including 1-anthracen-9-ylmethyl 3-methyl 2,2-dimethylmalonate and 1-(4-(3,5-dihydropyren-1-yl)butyl)-3-methyl 2,2-dimethylmalonate.
Versatile Organic Building Block
As an acid halide and carbonyl compound, it functions as a versatile building block in organic synthesis, enabling the construction of diverse molecular architectures.
| Molecular weight | 136.53 |
|---|---|
| Linear formula | CH3OCOCH2COCl |
| Assay | 97% |
| Boiling point | 57-59 °C/12 mmHg(lit.) |
| Density | 1.273 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.) |
| Storage temperature | 2-8°C |
| Application | Methyl 3-chloro-3-oxopropionate was used as a reagent in the synthesis of resin-bound 4-tosyl quinolinone1, 1-anthracen-9-ylmethyl 3-methyl 2,2-dimethylmalonate and 1-(4-(3,5-dihydropyren-1-yl)butyl)-3-methyl 2,2-dimethylmalonate2. |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 80 °C / 176 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3-chloro-3-oxopropionate used for?
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Methyl 3-chloro-3-oxopropionate (CAS 37517-81-0) is used as a reagent in organic synthesis, notably in the preparation of resin-bound quinolinones and complex malonate esters.
What are the CAS number and formula for Methyl 3-chloro-3-oxopropionate?
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The CAS number is 37517-81-0 and its linear formula is CH3OCOCH2COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3-chloro-3-oxopropionate with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should Methyl 3-chloro-3-oxopropionate be handled safely?
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This compound causes severe skin burns and eye damage (H314) and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Store at 2-8°C.
Is Methyl 3-chloro-3-oxopropionate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. Please contact us for export inquiries.
How can I request a sample or quote?
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To request a sample or a quote for Methyl 3-chloro-3-oxopropionate, please visit our website or contact our sales department directly.
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