R-(−)-Fluoxetine hydrochloride
R-(−)-Fluoxetine hydrochloride (CAS: 114247-09-5), with the molecular formula C17H18NOF3 · HCl and a molecular weight of 345.79 g/mol, is a white solid. It is primarily recognised as a selective serotonin reuptake inhibitor (SSRI). This compound is a valuable tool in neuroscientific research for studying serotonin pathways and their role in various physiological and behavioural processes.
- IUPAC
- (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride
- Synonyms
- (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride

Neuroscience Research
R-(−)-Fluoxetine hydrochloride is extensively utilized in research settings to investigate the function of serotonin transporters and their impact on neuronal signaling. It serves as a crucial reagent for studying mood disorders, behavioural science, and the mechanisms of neurotransmission.
Biochemical Studies
This compound is employed in biochemical assays to understand drug-receptor interactions and signalling pathways related to serotonin. Its specific action on serotonin reuptake makes it valuable for elucidating complex cellular processes.
GPCR Research
As a modulator of GPCR proteins, R-(−)-Fluoxetine hydrochloride is used in studies focusing on G protein-coupled receptors, particularly those involved in neurotransmission and cellular response mechanisms.
| Molecular weight | 345.79 |
|---|---|
| Empirical formula | C17H18NOF3 · HCl |
| Assay | >98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: soluble >10 mg/mL |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R-(−)-Fluoxetine hydrochloride used for?
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R-(−)-Fluoxetine hydrochloride is primarily used in research for its role as a selective serotonin reuptake inhibitor (SSRI), aiding in the study of neuroscience, cell biology, and neurotransmission.
What is the CAS number and formula for R-(−)-Fluoxetine hydrochloride?
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The CAS number is 114247-09-5 and the empirical formula is C17H18NOF3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R-(−)-Fluoxetine hydrochloride with a purity of >98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should R-(−)-Fluoxetine hydrochloride be handled?
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Due to its hazards (H302, H315, H318), handle with appropriate personal protective equipment including a dust mask (N95 US type), eyeshields, and gloves. Ensure good ventilation and avoid generating dust. Refer to the safety data sheet for full handling instructions.
Is R-(−)-Fluoxetine hydrochloride a controlled substance?
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The provided data does not indicate that R-(−)-Fluoxetine hydrochloride is a controlled substance.
How is R-(−)-Fluoxetine hydrochloride shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, capable of shipping and exporting R-(−)-Fluoxetine hydrochloride worldwide, adhering to all relevant regulations.
How can I request a sample or quote for R-(−)-Fluoxetine hydrochloride?
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Please contact our sales team via the website or direct inquiry to request a sample or a quote for R-(−)-Fluoxetine hydrochloride.
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