R(−)-Propylnorapomorphine hydrochloride
R(−)-Propylnorapomorphine hydrochloride (CAS: 18426-20-5), with the molecular formula C19H21NO2 · HCl and a molecular weight of 331.84 g/mol, is a chemical compound primarily utilised in neuroscience research. As a potent dopaminergic agonist, it serves as a valuable tool for studying dopamine receptor function and related signalling pathways. Its applications span in vitro and in vivo experimental models within the field of neuropharmacology.
- IUPAC
- R(−)-10,11-Dihydroxy-N-n-propylnoraporphine hydrochloride,R(−)-NPA hydrochloride
Neuroscience Research Tool
R(−)-Propylnorapomorphine hydrochloride is widely employed in neuroscience to investigate dopamine receptor subtypes and their roles in physiological and pathological processes. It acts as a selective agonist, enabling researchers to probe dopaminergic neurotransmission.
Dopaminergic System Studies
This compound facilitates the study of the dopaminergic system's involvement in various brain functions, including motor control, reward, and cognition. Its agonistic activity aids in understanding the impact of dopamine modulation.
GPCR Modulation Research
As a modulator of G protein-coupled receptors (GPCRs), specifically dopamine receptors, R(−)-Propylnorapomorphine hydrochloride is used in research focused on GPCR signalling pathways and drug discovery efforts targeting these receptors.
| Molecular weight | 331.84 |
|---|---|
| Empirical formula | C19H21NO2 · HCl |
| Form | solid |
| Colour | off-white |
| Solubility | 0.1 M HCl: soluble5-10 mg/mL (Solutions should be freshly prepared)methanol: soluble5-10 mg/mL (Solutions should be freshly prepared)H2O: moderately soluble (dissolve in oxygen-free boiled water containing 0.1% sodium metabisulfite or other antioxidants. Solutions should be freshly prepared.)alcohol: moderately soluble (Solutions should be freshly prepared.)aqueous base: insoluble |
| Optical activity | [α]22/D −70.3°, c = 0.17 in methanol(lit.) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD2(1813) |
|---|---|
| Absorption | εmax/273 nm, ethanol 17,400 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R(−)-Propylnorapomorphine hydrochloride used for?
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R(−)-Propylnorapomorphine hydrochloride is primarily used as a research tool in neuroscience to study the dopaminergic system, dopamine receptor function, and GPCR modulation.
What is the CAS number and formula for R(−)-Propylnorapomorphine hydrochloride?
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The CAS number is 18426-20-5, and the empirical formula is C19H21NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R(−)-Propylnorapomorphine hydrochloride for research purposes. Purity and assay details are specified on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should R(−)-Propylnorapomorphine hydrochloride be handled and stored?
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Handle R(−)-Propylnorapomorphine hydrochloride with appropriate personal protective equipment, including eyeshields and gloves. Store the compound at 2-8°C. Consult the Safety Data Sheet for comprehensive handling and safety information.
Is R(−)-Propylnorapomorphine hydrochloride a controlled substance?
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Based on the provided data, R(−)-Propylnorapomorphine hydrochloride is not explicitly listed as a controlled substance. However, users should always comply with local regulations regarding its possession and use.
How can I request a quote or sample of R(−)-Propylnorapomorphine hydrochloride?
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To request a quote or sample, please contact our sales team through the website or by phone. Our team will be happy to assist you with your inquiry.
How is R(−)-Propylnorapomorphine hydrochloride packed, shipped, and exported?
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R(−)-Propylnorapomorphine hydrochloride is carefully packed according to industry standards to ensure safe transport. We offer global export services and comply with all relevant international shipping regulations for chemical compounds.
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