R(+)-Verapamil monohydrochloride hydrate
R(+)-Verapamil monohydrochloride hydrate (CAS: 38176-02-2) is a white powder with a molecular weight of 491.06 g/mol (anhydrous basis). This chemical entity is a research chemical primarily employed in biological and biochemical studies. Its applications often involve investigating cellular processes, particularly in areas related to cell signaling, neuroscience, and drug transport mechanisms. Verapamil is known for its activity as a calcium channel blocker.
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Calcium Channel Blocker Research
Used in studies investigating the role of L-type calcium channels in cardiovascular and neuronal functions. It serves as a pharmacological tool to understand calcium ion influx.
Cell Signaling and Neuroscience Studies
Employed as a probe in cell biology to explore signaling pathways and neurotransmission. Its effects on ion channels are relevant for understanding cellular communication.
Drug Efflux Pump and Transporter Research
Utilised in research focused on multidrug resistance (MDR) and drug transport proteins. It can modulate the activity of certain efflux pumps, aiding the study of drug resistance mechanisms.
| Molecular weight | 491.06 (anhydrous basis) |
|---|---|
| Empirical formula | C27H38N2O4 · HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: >30 mg/mLethanol: soluble |
| Optical activity | [α]22/D +9.6°, c = 0.5 in ethanol(lit.) |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R(+)-Verapamil monohydrochloride hydrate used for?
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R(+)-Verapamil monohydrochloride hydrate is used in research settings, particularly in cell biology, neuroscience, and studies of drug transport mechanisms. It is known for its activity as a calcium channel blocker and its role in modulating drug efflux pumps.
What is the CAS number and chemical formula for R(+)-Verapamil monohydrochloride hydrate?
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The CAS number for the anhydrous form is 38176-02-2. The empirical formula is C27H38N2O4 · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R(+)-Verapamil monohydrochloride hydrate with an assay of ≥98% (HPLC). This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, or EP grade.
How should R(+)-Verapamil monohydrochloride hydrate be handled?
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This compound is classified as toxic if swallowed, in contact with skin, or if inhaled (H301-H311-H331). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Ensure good ventilation and avoid dust formation. Store desiccated.
Is R(+)-Verapamil monohydrochloride hydrate a controlled substance?
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The provided data does not indicate that R(+)-Verapamil monohydrochloride hydrate is a controlled substance.
How is R(+)-Verapamil monohydrochloride hydrate packed and shipped?
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R(+)-Verapamil monohydrochloride hydrate is supplied as a powder and is typically stored desiccated. Shipping and export procedures comply with relevant regulations for hazardous materials (UN 2811 6.1 / PGIII).
How can I request a sample or quote for R(+)-Verapamil monohydrochloride hydrate?
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To request a sample or obtain a quotation for R(+)-Verapamil monohydrochloride hydrate, please contact our sales department through the TSS website or by direct inquiry.
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