R-(−)-Apomorphine hydrochloride hemihydrate
R-(−)-Apomorphine hydrochloride hemihydrate (CAS: 41372-20-7) is a nonselective dopamine agonist, supplied by TSS with an assay of ≥98.5%. This white to gray crystalline powder, with the molecular formula C17H17NO2 · HCl · 1/2H2O and a molecular weight of 312.79 g/mol, exhibits anti-Parkinsonian and neuroprotective effects in vivo. It is a valuable reagent in neuroscience research, particularly for studying dopaminergic pathways and related cellular mechanisms.
Dopamine Receptor Agonism Research
As a nonselective dopamine agonist, R-(−)-Apomorphine hydrochloride hemihydrate is extensively used to investigate the function and modulation of dopamine receptors (DRD1-DRD5) in various biological systems and disease models.
Parkinson's Disease Research Tool
This compound's known anti-Parkinsonian effects in vivo make it a crucial tool for researchers studying the pathophysiology of Parkinson's disease and evaluating potential therapeutic strategies.
Neuroprotection Studies
R-(−)-Apomorphine hydrochloride hemihydrate demonstrates neuroprotective properties, enabling its use in research aimed at understanding mechanisms of neuronal damage and developing neuroprotective agents.
Cell Signaling and Neuroscience
Its role as a dopaminergic agent makes it relevant for studies on cell signaling pathways, neurotransmission, and broader neuroscience research, including those involving GPCR modulators.
| Molecular weight | 312.79 |
|---|---|
| Linear formula | C17H17NO2 · HCl · 1/2H2O |
| Assay | ≥98.5% |
| Form | calcined |
| Colour | white to gray |
| Solubility | H2O: ~10 mg/mL, clear, yellow-green |
| Application | R-(-)-Apomorphine hydrochloride hemihydrate is a nonselective dopamine agonist with anti-Parkinsonian and neuroprotective effects in vivo. |
| Melting point | 285-287 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816) |
|---|---|
| Storage Condition | protect from lightunder inert gas |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R-(−)-Apomorphine hydrochloride hemihydrate used for?
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R-(−)-Apomorphine hydrochloride hemihydrate is a nonselective dopamine agonist with anti-Parkinsonian and neuroprotective effects in vivo, primarily used in research applications within neuroscience, cell biology, and dopaminergic system studies.
What is the CAS number and chemical formula?
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The CAS number is 41372-20-7 and the chemical formula is C17H17NO2 · HCl · 1/2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R-(−)-Apomorphine hydrochloride hemihydrate with an assay of ≥98.5%. TSS does not represent this product as USP, BP, or EP grade.
How should R-(−)-Apomorphine hydrochloride hemihydrate be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves. This compound is acutely toxic if swallowed (H301) and requires careful handling to avoid exposure.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can export R-(−)-Apomorphine hydrochloride hemihydrate.
How can I request a quote or sample?
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Please contact our sales team directly to request a quote for R-(−)-Apomorphine hydrochloride hemihydrate or to inquire about obtaining a sample.
Does this chemical have any special storage requirements?
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Yes, R-(−)-Apomorphine hydrochloride hemihydrate should be stored protected from light and under an inert gas.
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