5-Chloro-6-methoxy-1-indanone
5-Chloro-6-methoxy-1-indanone (CAS: 344305-70-0) is a chemical compound with the molecular formula C10H9ClO2 and a molecular weight of 196.63 g/mol. This indanone derivative functions as a valuable building block in organic synthesis. It is primarily utilised as a reactant in the preparation of various organic compounds, including azaheterocycles and specific hydroxy derivatives, contributing to advancements in chemical synthesis and medicinal chemistry research.

Azaheterocycle Synthesis
Serves as a key reactant in palladium(II)-catalyzed ring-expansion reactions, facilitating the synthesis of complex azaheterocyclic structures.
Dopamine Receptor Ligand Precursors
Used in the preparation of phenyldihydroindene hydroxy derivatives, which are investigated as potential ligands for dopamine receptors.
Organic Synthesis Intermediate
A versatile building block for constructing more complex organic molecules due to its functionalised indanone core.
| Molecular weight | 196.63 |
|---|---|
| Empirical formula | C10H9ClO2 |
| Assay | 97% |
| Application | Reactant for:• Preparation of azaheterocycles via a palladium(II)-catalyzed ring-expansion reaction1• Preparation of phenyldihydroindene hydroxy derivatives as dopamine receptor ligands2 |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-6-methoxy-1-indanone used for?
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5-Chloro-6-methoxy-1-indanone is primarily used as a reactant in organic synthesis, particularly for the preparation of azaheterocycles and phenyldihydroindene hydroxy derivatives. It serves as a building block in chemical research and development.
What is the CAS number and chemical formula for 5-Chloro-6-methoxy-1-indanone?
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The CAS number for 5-Chloro-6-methoxy-1-indanone is 344305-70-0, and its chemical formula is C10H9ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-6-methoxy-1-indanone with a purity of 97% (assay). This product is suitable for research and general laboratory use. We do not represent this product as USP, BP, or EP grade.
How should 5-Chloro-6-methoxy-1-indanone be handled safely?
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5-Chloro-6-methoxy-1-indanone is classified as a Warning substance. It may be harmful if swallowed (H302) and can cause an allergic skin reaction (H317). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, face shields, and gloves, should be worn. Ensure adequate ventilation and avoid dust formation. Users should consult the full Safety Data Sheet (SDS) prior to handling.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all relevant international shipping regulations to ensure safe and compliant delivery.
How can I request a sample or quote for 5-Chloro-6-methoxy-1-indanone?
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To request a sample or a quotation for 5-Chloro-6-methoxy-1-indanone, please contact our sales department through the website or by phone.
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