5-Chloro-8-quinolinetrifluoromethanesulfonate
5-Chloro-8-quinolinetrifluoromethanesulfonate (CAS: 157437-38-2; C10H5ClF3NO3S) is a halogenated heterocyclic building block with a molecular weight of 311.66 g/mol. This compound, also known as 5-chloro-8-quinolinetriflate, is primarily utilised in chemical synthesis for the development of novel molecules. Its specific structural features make it a valuable intermediate in organic chemistry research and the production of specialised chemical entities.
- IUPAC
- 5-Chloro-8-quinolinetriflate

Organic Synthesis Intermediate
Serves as a key building block in multi-step organic synthesis pathways. Its reactive triflate group and substituted quinoline core allow for diverse chemical transformations.
Heterocyclic Chemistry Research
Utilised in academic and industrial research focused on the synthesis and functionalization of quinoline derivatives. It aids in exploring new chemical space for potential applications.
Pharmaceutical Intermediate Development
A potential precursor in the synthesis of complex molecules, including candidates for pharmaceutical research. Its structure may be incorporated into biologically active compounds.
| Molecular weight | 311.66 |
|---|---|
| Empirical formula | C10H5ClF3NO3S |
| Assay | 97% |
| Melting point | 79-83 °C(lit.) |

Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-8-quinolinetrifluoromethanesulfonate used for?
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5-Chloro-8-quinolinetrifluoromethanesulfonate is primarily used as a building block in organic synthesis and for research in heterocyclic chemistry, potentially serving as an intermediate in pharmaceutical development.
What is the CAS number and formula for 5-Chloro-8-quinolinetrifluoromethanesulfonate?
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The CAS number is 157437-38-2 and the empirical formula is C10H5ClF3NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a purity of 97% (assay). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations?
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This compound is classified as Danger. It is harmful if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator, should be used. Refer to the Safety Data Sheet for detailed handling instructions.
How is this chemical packed and shipped?
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This product is shipped as a dangerous good under UN 2811, Class 6.1, Packing Group III. TSS ensures compliant packaging and adherence to international shipping regulations for export.
How can I request a sample or quote?
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To request a sample or a quotation, please contact the TSS sales team through our website or by phone, providing the product name and CAS number.
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