5-Chloro-7-iodo-8-quinolinol
5-Chloro-7-iodo-8-quinolinol (CAS: 130-26-7) is a halogenated heterocyclic compound with the molecular formula C9H5ClINO and a molecular weight of 305.50 g/mol. It presents as a chemical intermediate and building block, primarily utilised in chemical synthesis and analytical applications. Its structure, featuring both chlorine and iodine substituents on a quinoline core, makes it a valuable component in constructing more complex molecules for research and development purposes.
- IUPAC
- 5-Chloro-8-hydroxy-7-iodoquinoline,Clioquinol,Iodochlorhydroxyquin
- Synonyms
- 5-Chloro-8-hydroxy-7-iodoquinolineClioquinolIodochlorhydroxyquin

Analytical Reagent
5-Chloro-7-iodo-8-quinolinol has been employed in analytical studies, specifically for its use in the analysis of intracellular free zinc ions. This application leverages fluorescence microscopy techniques when used in conjunction with probes like FluoZin-3.
Chemical Synthesis
As a halogenated heterocyclic building block, this compound serves as a crucial intermediate in organic synthesis. Its reactive sites allow for further chemical modifications, enabling the creation of novel molecular structures for various research endeavours.
Research and Development
This quinoline derivative is suitable for use in research and development settings. Its specific chemical properties can be exploited in the exploration of new chemical pathways and the synthesis of potential drug candidates or functional materials.
| Molecular weight | 305.50 |
|---|---|
| Empirical formula | C9H5ClINO |
| Assay | ≥95.0% (HPLC) |
| Solubility | dioxane: soluble0.5 g/10 mL, clear, faintly yellow to yellow |
| Application | 5-Chloro-7-iodo-8-quinolinol has been used in analysis of intracellular free zinc ions with the FluoZin-3 probes using fluorescence microscopy1. |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-7-iodo-8-quinolinol used for?
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5-Chloro-7-iodo-8-quinolinol is used as a building block in chemical synthesis and for analytical purposes, such as in the analysis of intracellular free zinc ions.
What is the CAS number and molecular formula for 5-Chloro-7-iodo-8-quinolinol?
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The CAS number is 130-26-7, and the molecular formula is C9H5ClINO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-7-iodo-8-quinolinol with an assay of ≥95.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Chloro-7-iodo-8-quinolinol be handled safely?
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5-Chloro-7-iodo-8-quinolinol is classified as toxic if swallowed (H301) and requires appropriate safety measures. Use with adequate ventilation and wear Eyeshields, Faceshields, Gloves, and a P2 respirator cartridge. In case of accidental ingestion, seek immediate medical attention (P301 + P310).
How is 5-Chloro-7-iodo-8-quinolinol shipped and exported?
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This compound is shipped and exported under UN 2811, Hazard Class 6.1, Packing Group III regulations.
How can I request a sample or quote for 5-Chloro-7-iodo-8-quinolinol?
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To request a sample or obtain a quote, please contact our sales department via the website or by phone.
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