5-Chloro-6-hydroxynicotinic acid
5-Chloro-6-hydroxynicotinic acid (CAS: 54127-63-8) is a chlorinated pyridine derivative with the molecular formula C6H4ClNO3 and a molecular weight of 173.55 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within the domain of halogenated heterocycles. Its primary application involves its use in the preparation of triorganotin compounds, highlighting its utility in organic chemistry research and development.
- IUPAC
- 5-Chloro-6-hydroxypyridine-3-carboxylicacid
Preparation of Triorganotin Compounds
5-Chloro-6-hydroxynicotinic acid is employed in the synthesis of various triorganotin compounds. It reacts with (R3Sn)2O, where R can be phenyl, 2-chlorobenzyl, 2-fluorobenzyl, or 4-cyanobenzyl groups, enabling the formation of complex organometallic structures.
Halogenated Heterocycle Synthesis
As a key intermediate within the halogenated heterocycles category, this compound facilitates the construction of complex molecular architectures containing pyridine rings functionalised with chlorine and hydroxyl groups.
Research and Development Chemical
This chemical is utilised in research laboratories for developing new synthetic methodologies and exploring novel chemical entities, contributing to advancements in medicinal chemistry and materials science.
| Molecular weight | 173.55 |
|---|---|
| Empirical formula | C6H4ClNO3 |
| Assay | ≥97.0% |
| Application | 5-Chloro-6-hydroxynicotinic acid has been used in the preparation of triorganotin compounds via reaction with (R3Sn)2O (R=Ph, 2-ClC6H4CH2, 2-FC6H4CH2, 4-CNC6H4CH2)1. |
| Melting point | ≥300 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-6-hydroxynicotinic acid used for?
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5-Chloro-6-hydroxynicotinic acid is primarily used as a building block in chemical synthesis, notably in the preparation of triorganotin compounds and other halogenated heterocyclic structures for research and development.
What is the CAS number and molecular formula for 5-Chloro-6-hydroxynicotinic acid?
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The CAS number is 54127-63-8, and the molecular formula is C6H4ClNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-6-hydroxynicotinic acid with a minimum purity of 97.0%. This product is suitable for chemical synthesis and research purposes. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for 5-Chloro-6-hydroxynicotinic acid?
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5-Chloro-6-hydroxynicotinic acid is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask (N95 type), eyeshields, and gloves. Handle in a well-ventilated area.
How is 5-Chloro-6-hydroxynicotinic acid shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including 5-Chloro-6-hydroxynicotinic acid, adhering to all necessary international shipping and export regulations.
How can I request a sample or quote for 5-Chloro-6-hydroxynicotinic acid?
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To request a sample or a quote for 5-Chloro-6-hydroxynicotinic acid, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your inquiry.
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