3-Benzyloxybenzoyl chloride
3-Benzyloxybenzoyl chloride (CAS: 61535-46-4, C14H11ClO2) is an organic acid halide with a molecular weight of 246.69. This compound serves as a key reactant in the synthesis of various complex organic molecules. Its applications include the preparation of dihydroquinolinones and tetrahydroquinazolinones with potential antitumor activity, as well as carbamate derivatives investigated as fatty acid amide hydrolase inhibitors. Available at 94% assay, it is a valuable building block for chemical research and development.
- IUPAC
- 3-Benzyloxybenzoic acid chloride
- Synonyms
- 3-Benzyloxybenzoic acid chloride
Preparation of Antitumor Agents
Serves as a crucial reactant in the synthesis of dihydroquinolinones and tetrahydroquinazolinones, which have shown potential as kinesin spindle protein inhibitors and antitumor agents. This application highlights its role in medicinal chemistry research.
Synthesis of Enzyme Inhibitors
Utilised in the preparation of carbamate derivatives. These derivatives are explored for their inhibitory effects on fatty acid amide hydrolase (FAAH), suggesting potential therapeutic applications in managing certain physiological conditions.
Organic Synthesis Building Block
As an acid halide, 3-Benzyloxybenzoyl chloride is a versatile building block in organic synthesis, enabling the introduction of the 3-benzyloxybenzoyl moiety into various molecular structures for further chemical exploration.
| Molecular weight | 246.69 |
|---|---|
| Empirical formula | C14H11ClO2 |
| Assay | 94% |
| Application | Reactant for:• Preparation of dihydroquinolinones and tetrahydroquinazolinones as potent kinesin spindle protein inhibitors and potential antitumor agents1• Preparation of carbamate derivatives as fatty acid amide hydrolase inhibitors2 |
| Melting point | 40-43 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3261 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 34-50/53 |
| Safety statements (S) | 26-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Benzyloxybenzoyl chloride used for?
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3-Benzyloxybenzoyl chloride is used as a reactant in the preparation of dihydroquinolinones and tetrahydroquinazolinones with potential antitumor activity, and in the preparation of carbamate derivatives as fatty acid amide hydrolase inhibitors. It also serves as a general building block in organic synthesis.
What is the CAS number and formula for 3-Benzyloxybenzoyl chloride?
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The CAS number for 3-Benzyloxybenzoyl chloride is 61535-46-4, and its molecular formula is C14H11ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Benzyloxybenzoyl chloride with an assay of 94%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for 3-Benzyloxybenzoyl chloride?
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3-Benzyloxybenzoyl chloride is classified as Danger, causing severe skin burns and eye damage (H314) and is very toxic to aquatic life (H400). It requires the use of personal protective equipment including Eyeshields, Faceshields, Gloves, and appropriate respiratory protection. Handle with extreme caution in a well-ventilated area.
How is 3-Benzyloxybenzoyl chloride packed and shipped?
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3-Benzyloxybenzoyl chloride is shipped as UN 3261, Class 8, Packing Group II. Please contact our export department for specific packaging and shipping details relevant to your region.
How can I request a sample or quote for 3-Benzyloxybenzoyl chloride?
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To request a sample or a quote for 3-Benzyloxybenzoyl chloride, please use the 'Enquire' button on our product page or contact our sales team directly.
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