5-Chloro-4-nitro-o-toluidine
5-Chloro-4-nitro-o-toluidine (CAS: 13852-51-2), with the molecular formula ClC6H2(NO2)(CH3)NH2 and a molecular weight of 186.60 g/mol, is a chemical intermediate. It is a nitrogen compound used in chemical synthesis. This substance is typically supplied as a technical or research grade material by Tech Serve Solutions, and its primary known application involves its use in the synthesis of specific dioxin derivatives.
- IUPAC
- 2-Amino-4-chloro-5-nitrotoluene,5-Chloro-2-methyl-4-nitroaniline
- Synonyms
- 2-Amino-4-chloro-5-nitrotoluene5-Chloro-2-methyl-4-nitroaniline

Synthesis of Dioxin Derivatives
5-Chloro-4-nitro-o-toluidine has been utilised as a precursor in the synthesis of 2-substituted 3,7,8-trichlorodibenzo-p-dioxins. This application highlights its role as a building block in complex organic synthesis.
Organic Building Block
As a substituted aniline, this compound serves as a versatile building block in organic chemistry. Its functional groups (amine, nitro, and chloro) allow for various chemical transformations and the construction of more complex molecular structures.
Chemical Synthesis
The compound is employed in various chemical synthesis pathways, contributing to the development of novel compounds. Its structure makes it suitable for reactions involving aromatic substitution and functional group manipulation.
| Molecular weight | 186.60 |
|---|---|
| Linear formula | ClC6H2(NO2)(CH3)NH2 |
| Assay | 40% |
| Contains / stabiliser | ~60% water |
| Application | 5-Chloro-4-nitro-o-toluidine was used in the synthesis of 2-substituted 3,7,8-trichlorodibenzo-p-dioxins1. |
| Melting point | 164-167 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-4-nitro-o-toluidine used for?
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5-Chloro-4-nitro-o-toluidine is used in chemical synthesis, particularly as a building block in the preparation of certain organic compounds, including 2-substituted 3,7,8-trichlorodibenzo-p-dioxins.
What is the CAS number and chemical formula for 5-Chloro-4-nitro-o-toluidine?
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The CAS number is 13852-51-2, and the chemical formula is ClC6H2(NO2)(CH3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-4-nitro-o-toluidine with an assay of approximately 40%, containing about 60% water. It is generally considered a technical or research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations for handling 5-Chloro-4-nitro-o-toluidine?
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5-Chloro-4-nitro-o-toluidine is classified with the GHS07 symbol and carries a Warning signal word. It has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type ABEK respirator filter), should be used. Handle in a well-ventilated area.
How is 5-Chloro-4-nitro-o-toluidine packed, shipped, and exported?
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5-Chloro-4-nitro-o-toluidine is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions, a specialist supplier.
How can I request a quote or sample for 5-Chloro-4-nitro-o-toluidine?
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To request a quote or sample of 5-Chloro-4-nitro-o-toluidine, please contact the Tech Serve Solutions sales team through our website or by phone. We are equipped to handle inquiries for research and industrial needs.
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