4-Fluoro-2-nitroanisole
4-Fluoro-2-nitroanisole (CAS: 445-83-0), with the molecular formula FC6H3(NO2)OCH3 and a molecular weight of 171.13 g/mol, is a fluorinated aromatic compound. It functions as a valuable building block in organic synthesis. Its structure, featuring both a nitro group and a fluorine atom on an anisole ring, allows for diverse chemical transformations, making it a useful intermediate in the development of new materials and active pharmaceutical ingredients. TSS supplies this compound with an assay of 98%.

Organic Synthesis Intermediate
4-Fluoro-2-nitroanisole serves as a key intermediate in the synthesis of complex organic molecules. Its reactive nitro and fluoro functionalities can be selectively modified or displaced to construct novel chemical entities.
Pharmaceutical Research
This compound is utilised in pharmaceutical research and development for the creation of new drug candidates. The presence of fluorine can influence pharmacokinetic properties, making it attractive for medicinal chemistry applications.
Material Science
As a fluorinated organic building block, 4-Fluoro-2-nitroanisole may find applications in the development of advanced materials, where the incorporation of fluorine can impart specific properties such as thermal stability or altered electronic characteristics.
| Molecular weight | 171.13 |
|---|---|
| Linear formula | FC6H3(NO2)OCH3 |
| Assay | 98% |
| Melting point | 62-64 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-nitroanisole used for?
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4-Fluoro-2-nitroanisole is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and material science development.
What are the CAS number and formula for 4-Fluoro-2-nitroanisole?
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The CAS number is 445-83-0 and the molecular formula is FC6H3(NO2)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-2-nitroanisole with a purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Fluoro-2-nitroanisole be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the Safety Data Sheet for full details.
Is 4-Fluoro-2-nitroanisole a controlled substance?
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The provided data does not indicate that 4-Fluoro-2-nitroanisole is a controlled substance.
How is 4-Fluoro-2-nitroanisole packed, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and adherence to all shipping and export regulations for chemicals like 4-Fluoro-2-nitroanisole.
How can I request a quote or sample of 4-Fluoro-2-nitroanisole?
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To request a quote or sample, please contact our sales department through the Tech Serve Solutions website or your dedicated account manager.
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