4-Fluoro-2-methylphenylmagnesium bromide solution
4-Fluoro-2-methylphenylmagnesium bromide solution (CAS 30897-90-6) is an organometallic compound with the linear formula FC₆H₃(CH₃)MgBr and a molecular weight of 213.33 g/mol. Supplied as a 0.5 M solution in THF, this Grignard reagent serves as a versatile building block in organic synthesis, facilitating the formation of new carbon-carbon bonds. Its utility spans various chemical transformations, particularly in the preparation of complex organic molecules for research and development.
Organometallic Synthesis
As a Grignard reagent, it is extensively used in nucleophilic addition reactions with aldehydes, ketones, esters, and nitriles to form new C-C bonds. This is fundamental in constructing more complex organic structures.
Pharmaceutical Intermediate Production
The introduction of the 4-fluoro-2-methylphenyl moiety is a key step in synthesising various pharmaceutical intermediates. Its reactivity allows for controlled incorporation into target drug molecules.
Materials Science
Organometallic reagents like this can be employed in the synthesis of specialised polymers or organic materials where specific aryl substituents are required for desired electronic or physical properties.
Agrochemical Development
It can serve as a precursor in the development of novel agrochemicals, where the specific fluorinated and methylated phenyl group may confer desired biological activity or stability.
| Molecular weight | 213.33 |
|---|---|
| Linear formula | FC6H3(CH3)MgBr |
| Boiling point | 65 °C |
| Density | 0.958 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-methylphenylmagnesium bromide solution used for?
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This solution is a Grignard reagent primarily used as a versatile building block in organic synthesis for forming new carbon-carbon bonds, particularly in the preparation of pharmaceutical intermediates, agrochemicals, and specialised organic materials.
What is the CAS number and formula for this product?
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The CAS number is 30897-90-6, and its linear formula is FC₆H₃(CH₃)MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this reagent as a 0.5 M solution in THF. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade; it is suitable for research and chemical synthesis applications.
How should 4-Fluoro-2-methylphenylmagnesium bromide solution be handled and stored?
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This product is a flammable liquid and vapour, causes serious eye irritation, and may cause respiratory irritation. It can also form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from heat and ignition sources. Store refrigerated at 2-8°C in a tightly sealed container to prevent peroxide formation and moisture ingress.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Fluoro-2-methylphenylmagnesium bromide solution, and can arrange for international shipment.
How can I request a sample or quote?
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To request a sample or a quote for 4-Fluoro-2-methylphenylmagnesium bromide solution, please contact our sales team via the website or by telephone, providing your contact details and the quantity required.
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