5-Methoxyindole-2-carboxylic acid ethyl ester
Ethyl 5-methoxyindole-2-carboxylate (CAS 4792-58-9) is a chemical compound with the molecular formula C12H13NO3 and a molecular weight of 219.24 g/mol. This indole derivative serves as a key building block in organic synthesis. Its primary utility lies in its role as a reactant for the preparation of various complex molecules, including pharmaceutical intermediates and advanced research chemicals, contributing to the development of novel therapeutic agents and advanced materials.
- IUPAC
- 2-Carbethoxy-5-methoxyindole,2-Ethoxycarbonyl-5-methoxyindole,Ethyl 5-methoxyindole-2-carboxylate,NSC 30929
- Synonyms
- 2-Carbethoxy-5-methoxyindole2-Ethoxycarbonyl-5-methoxyindoleEthyl 5-methoxyindole-2-carboxylateNSC 30929

Ligand Synthesis for GABA Receptor Binding
This compound is utilized as a reactant in the synthesis of novel ligands designed to exhibit specific binding affinities towards the GABA receptor, a crucial target in neurological research and therapeutic development.
Development of SGLT2 Inhibitors
It serves as a precursor in the synthetic pathways for Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors, which are important in managing hyperglycemia in patients with diabetes.
Anticancer Agent Research
The molecule acts as a building block for the development of potential anticancer agents, contributing to the ongoing research for new oncology treatments.
HIV-1 Integrase Inhibitor Synthesis
It is employed in the synthesis of HIV-1 integrase inhibitors, a class of drugs critical in the management of HIV infection by blocking viral replication.
Inhibitor of Proliferation of Colon Cancer Cells
This chemical is used as a reactant in the creation of compounds that inhibit the proliferation of colon cancer cells, advancing research in colorectal cancer therapeutics.
| Molecular weight | 219.24 |
|---|---|
| Empirical formula | C12H13NO3 |
| Storage temperature | −20°C |
| Application | Reactant for preparation of:• Ligands with binding specificity towards the GABA receptor1• Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes2• Anticancer agents3• Integrase strand-transfer inhibitors (INSTIs)4• Inhibitor of Proliferation of Colon Cancer Cells5• Isomeridianin G as GSK-3? inhibitors6• HIV-1 integrase inhibitors7• Inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)8 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 5-methoxyindole-2-carboxylate used for?
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Ethyl 5-methoxyindole-2-carboxylate is used as a reactant in the preparation of various molecules, including ligands for GABA receptors, SGLT2 inhibitors for diabetes management, anticancer agents, HIV-1 integrase inhibitors, and other bioactive compounds.
What are the CAS number and formula for Ethyl 5-methoxyindole-2-carboxylate?
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The CAS number for Ethyl 5-methoxyindole-2-carboxylate is 4792-58-9, and its empirical formula (Hill notation) is C12H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 5-methoxyindole-2-carboxylate as a research-grade chemical. We do not represent it as USP, BP, EP, or for any pharmacopoeia, nutraceutical, or food applications unless explicitly stated in the product specifications.
How should Ethyl 5-methoxyindole-2-carboxylate be handled and stored?
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Based on its WGK Germany classification of 3, Ethyl 5-methoxyindole-2-carboxylate is considered hazardous to water. It should be handled with appropriate personal protective equipment in a well-ventilated area, and stored at -20°C as recommended.
Does TSS export Ethyl 5-methoxyindole-2-carboxylate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Ethyl 5-methoxyindole-2-carboxylate, serving customers worldwide.
How can I request a sample or quote for Ethyl 5-methoxyindole-2-carboxylate?
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To request a sample or obtain a quote for Ethyl 5-methoxyindole-2-carboxylate, please contact our sales department through the website or by phone, providing the product name and CAS number.
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