5-Methoxyindole-3-carboxaldehyde
5-Methoxyindole-3-carboxaldehyde (CAS: 10601-19-1; Formula: C10H9NO2; Molar Mass: 175.18 g/mol) is a heterocyclic organic compound utilised as a versatile building block in chemical synthesis. Its indole core, functionalised with a methoxy group and an aldehyde moiety, enables its participation in a variety of reactions. It serves as a key reactant in the preparation of diverse molecules, including potential therapeutic agents and fluorescent probes.
- IUPAC
- 3-Formyl-5-methoxyindole,NSC 521754
- Synonyms
- 3-Formyl-5-methoxyindole5-Methoxy-1H-indole-3-carbaldehyde5-Methoxyindole-3-carbaldehyde
Synthesis of Tryptophan Dioxygenase Inhibitors
5-Methoxyindole-3-carboxaldehyde acts as a crucial reactant in the synthesis of compounds investigated for their potential as anticancer immunomodulators by inhibiting tryptophan dioxygenase.
Preparation of Imidazopyridines and Imidazobenzothiazoles
This indole derivative is employed as a reactant in the preparation of complex heterocyclic systems such as imidazopyridines and imidazobenzothiazoles, valuable scaffolds in medicinal chemistry.
Development of Fluorescent Neuroactive Probes
The compound serves as a reactant in the preparation of specialised fluorescent probes designed for brain imaging, aiding in the study of neuroactive substances.
Synthesis of Antibacterial Agents
5-Methoxyindole-3-carboxaldehyde is utilised as a reactant in the synthetic pathways leading to novel antibacterial agents.
Preparation of Antiandrogens
It functions as a reactant in the synthesis of compounds being explored for their potential as antiandrogenic agents.
| Molecular weight | 175.18 |
|---|---|
| Empirical formula | C10H9NO2 |
| Assay | ≥99% |
| Application | • reactant in synthesis of tryptophan dioxygenase inhibitors as potential anticancer immunomodulators1• reactant in preparation of inhibitor of the C-terminal domain of RNA polymerase II• reactant in preparation of imidazopyridines and imidazobenzothiazoles2• reactant in preparation of fluorescent neuroactive probes for brain imaging3• reactant in preparation of antibacterial agents4• reactant in synthesis of antiandrogens5 |
| Melting point | 179-183 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxyindole-3-carboxaldehyde used for?
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5-Methoxyindole-3-carboxaldehyde is used as a reactant in the synthesis of various organic molecules, including potential anticancer immunomodulators, inhibitors of RNA polymerase II, imidazopyridines, imidazobenzothiazoles, fluorescent neuroactive probes, antibacterial agents, and antiandrogens.
What are the CAS number and formula for 5-Methoxyindole-3-carboxaldehyde?
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The CAS number is 10601-19-1, and the molecular formula is C10H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxyindole-3-carboxaldehyde with a purity of ≥99%. This product is suitable for research and chemical synthesis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Methoxyindole-3-carboxaldehyde be handled?
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5-Methoxyindole-3-carboxaldehyde is classified as a warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash skin thoroughly after handling. If in eyes, rinse cautiously with water for several minutes; remove contact lenses if present and easy to do. Continue rinsing.
How is 5-Methoxyindole-3-carboxaldehyde packed and shipped?
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5-Methoxyindole-3-carboxaldehyde is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 5-Methoxyindole-3-carboxaldehyde?
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To request a sample or a quotation for 5-Methoxyindole-3-carboxaldehyde, please contact the Tech Serve Solutions sales team through our website or by calling our office.
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