5-Methoxyindole-2-carboxylic acid
5-Methoxyindole-2-carboxylic acid (CAS: 4382-54-1), with the molecular formula C10H9NO3 and a molecular weight of 191.18 g/mol, is a valuable indole derivative. This compound serves as a key reactant in the synthesis of diverse biologically active molecules. Its applications span the development of novel anticancer agents, fluorescent probes for in vivo imaging, and ligands for various receptor targets, highlighting its significance in medicinal chemistry and drug discovery research.
- IUPAC
- NSC 30927
Anticancer Agent Synthesis
5-Methoxyindole-2-carboxylic acid is utilised as a precursor in the preparation of potent antitumor bifunctional DNA alkylating agents. Its structure is integral to developing novel therapeutic strategies against cancer.
Fluorescent Probe Development
This compound is employed in the synthesis of fluorescent small molecule probes. These probes are designed for in vivo lipid imaging, offering advanced capabilities for biological research and diagnostics.
Receptor Ligand Synthesis
It serves as a building block for developing selective ligands for important biological targets, including Dopamine D3 and 5-HT4 receptors. This application is crucial for understanding neurological pathways and developing related therapeutics.
Inhibitor Synthesis
5-Methoxyindole-2-carboxylic acid is a reactant in the synthesis of various inhibitors, such as Indoleamine 2,3-dioxygenase (IDO) inhibitors and inhibitors of Mycobacterium tuberculosis pantothenate synthetase.
| Molecular weight | 191.18 |
|---|---|
| Empirical formula | C10H9NO3 |
| Assay | 97% |
| Application | Reactant for preparation of:• Anticancer agents1• A fluorescent small molecule probe for in vivo lipid imaging2• Indoleamine 2,3-dioxygenase (IDO) inhibitors3• Selective Dopamine D3 receptor ligands4• 5-HT4 receptor ligands5• Inhibitors of Mycobacterium tuberculosis pantothenate synthetase6• Hypoxia selective cytotoxins7• Potent antitumor bifunctional DNA alkylating agents8 |
| Melting point | 199-201 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxyindole-2-carboxylic acid used for?
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5-Methoxyindole-2-carboxylic acid is primarily used as a reactant in the synthesis of various biologically active compounds, including anticancer agents, fluorescent probes for lipid imaging, indoleamine 2,3-dioxygenase (IDO) inhibitors, and selective receptor ligands.
What are the CAS number and molecular formula for 5-Methoxyindole-2-carboxylic acid?
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The CAS number for 5-Methoxyindole-2-carboxylic acid is 4382-54-1, and its molecular formula is C10H9NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxyindole-2-carboxylic acid with an assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations when handling 5-Methoxyindole-2-carboxylic acid?
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When handling 5-Methoxyindole-2-carboxylic acid, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3.
How is 5-Methoxyindole-2-carboxylic acid packed, shipped, and exported?
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5-Methoxyindole-2-carboxylic acid is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in global export, adhering to all necessary regulations for chemical shipments.
How can I request a sample or quote for 5-Methoxyindole-2-carboxylic acid?
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To request a sample or a quote for 5-Methoxyindole-2-carboxylic acid, please contact our sales team through the website or by phone, providing your specific requirements.
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