2-(Trimethylacetyl)thiophene
2-(Trimethylacetyl)thiophene (CAS: 20409-48-7), with the molecular formula C9H12OS and a molecular weight of 168.26 g/mol, is a versatile thiophene derivative. It serves as a valuable building block in organic synthesis, particularly for constructing complex heterocyclic compounds. Its chemical structure lends itself to various applications within chemical research and development, contributing to the advancement of new materials and pharmaceuticals.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its thiophene core and acetyl group offer reactive sites for diverse chemical transformations.
Heterocyclic Chemistry
Serves as a fundamental building block for creating novel heterocyclic compounds, specifically those incorporating the thiophene moiety. This is crucial in the development of new chemical entities.
Pharmaceutical Research
A potential precursor or intermediate in the research and development of pharmaceutical agents. Its structure can be incorporated into drug candidates targeting various therapeutic areas.
Materials Science
Investigated for use in materials science, where thiophene derivatives can contribute to the development of functional materials with unique electronic or optical properties.
| Molecular weight | 168.26 |
|---|---|
| Empirical formula | C9H12OS |
| Assay | 97% |
| Boiling point | 114-116 °C/14 mmHg |
| Density | 1.070 g/mL at 25 °C |
| Refractive index | n20/D 1.536 |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trimethylacetyl)thiophene used for?
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2-(Trimethylacetyl)thiophene is primarily used as an intermediate and building block in organic synthesis, particularly in the fields of heterocyclic chemistry, pharmaceutical research, and materials science.
What are the CAS number and formula for 2-(Trimethylacetyl)thiophene?
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The CAS number for 2-(Trimethylacetyl)thiophene is 20409-48-7, and its molecular formula is C9H12OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trimethylacetyl)thiophene with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 2-(Trimethylacetyl)thiophene be handled safely?
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When handling 2-(Trimethylacetyl)thiophene, it is advisable to wear a dust mask type N95 (US), eyeshields, face shields, and gloves. It is harmful if swallowed and may cause an allergic skin reaction (H302, H317).
Is 2-(Trimethylacetyl)thiophene available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Trimethylacetyl)thiophene, and can accommodate international requests.
How can I request a sample or quote for 2-(Trimethylacetyl)thiophene?
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To request a sample or quote for 2-(Trimethylacetyl)thiophene, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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