4-Fluoro-2-nitrophenol
4-Fluoro-2-nitrophenol (CAS: 394-33-2), with the molecular formula FC<sub>6</sub>H<sub>3</sub>(NO<sub>2</sub>)OH and a molecular weight of 157.10 g/mol, is a key organic intermediate. This compound serves as a versatile building block in various chemical syntheses, particularly within the pharmaceutical and agrochemical sectors. Its specific structure, featuring both a fluorine atom and a nitro group on a phenol ring, enables diverse downstream functionalisation and incorporation into complex molecular architectures.
Pharmaceutical Intermediate
4-Fluoro-2-nitrophenol is utilised in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated and nitrated phenolic structure allows for the introduction of specific functionalities required for targeted drug development.
Agrochemical Synthesis
This compound can serve as a precursor in the development of new agrochemicals. The presence of fluorine often enhances the efficacy and metabolic stability of pesticides and herbicides.
Organic Synthesis Building Block
As a difunctionalised aromatic compound, it is employed in general organic synthesis for creating more complex molecules. Its reactivity can be leveraged for various coupling and substitution reactions.
Research and Development
It is a valuable reagent for academic and industrial research laboratories exploring novel chemical entities and synthetic methodologies.
| Molecular weight | 157.10 |
|---|---|
| Linear formula | FC6H3(NO2)OH |
| Assay | 99% |
| Melting point | 75-77 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-nitrophenol primarily used for?
+
4-Fluoro-2-nitrophenol is principally used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and as a general building block in organic chemistry.
What are the CAS number and molecular formula for 4-Fluoro-2-nitrophenol?
+
The CAS number is 394-33-2 and the molecular formula is FC<sub>6</sub>H<sub>3</sub>(NO<sub>2</sub>)OH.
What grade and purity does Tech Serve Solutions supply for 4-Fluoro-2-nitrophenol?
+
Tech Serve Solutions supplies 4-Fluoro-2-nitrophenol with a purity of 99% (assay). We do not represent this product as USP, BP, or EP grade.
How should 4-Fluoro-2-nitrophenol be handled safely?
+
4-Fluoro-2-nitrophenol is harmful if swallowed, in contact with skin, or if inhaled. It causes skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
Is 4-Fluoro-2-nitrophenol exported or shipped by TSS?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Fluoro-2-nitrophenol.
How can I request a quote or sample of 4-Fluoro-2-nitrophenol?
+
Please contact our sales team via the website or phone to request a quote or a sample of 4-Fluoro-2-nitrophenol.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis