4-Fluoro-2-nitrotoluene
4-Fluoro-2-nitrotoluene (CAS 446-10-6; Formula CH3C6H3(NO2)F) is a fluorinated aromatic compound with a molecular weight of 155.13. This chemical serves as a valuable intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its specific structural features allow for diverse chemical transformations, making it a key building block for more complex molecules.

Pharmaceutical Synthesis
Utilised as a precursor in the synthesis of active pharmaceutical ingredients (APIs). The presence of both a nitro and a fluorine group offers versatile reaction pathways for drug discovery and development.
Agrochemical Intermediates
Serves as a building block for the creation of novel pesticides, herbicides, and fungicides. Its fluorinated structure can impart desirable properties to agrochemical products.
Specialty Chemicals
Employed in the production of various specialty organic chemicals. Its reactive sites facilitate its incorporation into diverse molecular structures for advanced material applications.
| Molecular weight | 155.13 |
|---|---|
| Linear formula | CH3C6H3(NO2)F |
| Assay | 98% |
| Boiling point | 138-139 °C/83 mmHg(lit.) |
| Refractive index | n20/D 1.522(lit.) |
| Melting point | 27 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-nitrotoluene used for?
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4-Fluoro-2-nitrotoluene is primarily used as an intermediate in organic synthesis, with significant applications in the pharmaceutical and agrochemical sectors for the development of new active ingredients and crop protection agents.
What are the CAS number and formula for 4-Fluoro-2-nitrotoluene?
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The CAS number for 4-Fluoro-2-nitrotoluene is 446-10-6, and its chemical formula is CH3C6H3(NO2)F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-2-nitrotoluene with a minimum assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 4-Fluoro-2-nitrotoluene be handled safely?
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4-Fluoro-2-nitrotoluene is classified as harmful if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves in a well-ventilated area.
Does Tech Serve Solutions export 4-Fluoro-2-nitrotoluene?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Fluoro-2-nitrotoluene, and can cater to international shipping requirements.
How can I request a quote or sample for 4-Fluoro-2-nitrotoluene?
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To request a quote or sample of 4-Fluoro-2-nitrotoluene, please contact our sales team through the website or by phone, providing your specific requirements.
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