4-Fluoro-2-nitrophenyl isocyanate
4-Fluoro-2-nitrophenyl isocyanate (CAS 190774-51-7, FC6H3(NO2)NCO) is a chemical intermediate with a molecular weight of 182.11 g/mol. This compound serves as a versatile building block in organic synthesis, particularly for introducing the 4-fluoro-2-nitrophenyl moiety into larger molecules. Its reactive isocyanate group enables participation in a variety of chemical transformations, making it valuable for researchers and manufacturers in fields requiring specialised organic compounds.

Organic Synthesis Intermediate
This compound is a key building block for synthesising complex organic molecules. The reactive isocyanate group readily undergoes addition reactions with nucleophiles like amines and alcohols.
Pharmaceutical Research
Used in the development of novel pharmaceutical candidates, where its specific functional groups can be incorporated to modulate biological activity or pharmacokinetic properties.
Material Science
Potentially employed in the synthesis of specialised polymers or functional materials where the fluoro-nitrophenyl structure imparts desired characteristics.
| Molecular weight | 182.11 |
|---|---|
| Linear formula | FC6H3(NO2)NCO |
| Assay | 95% |
| Melting point | 52-56 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-nitrophenyl isocyanate used for?
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4-Fluoro-2-nitrophenyl isocyanate is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and the development of specialised organic compounds.
What are the CAS number and chemical formula for 4-Fluoro-2-nitrophenyl isocyanate?
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The CAS number is 190774-51-7, and the chemical formula is FC6H3(NO2)NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-2-nitrophenyl isocyanate with an assay of 95%. This product is intended for research and laboratory use, and we do not represent it as USP, BP, EP, or any pharmacopoeia grade.
How should 4-Fluoro-2-nitrophenyl isocyanate be handled safely?
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Due to its hazardous nature (Danger signal word; H302, H312, H315, H319, H332, H334, H335), handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, face shields, and gloves. Ensure adequate ventilation. Avoid inhalation of dust and contact with skin and eyes.
How is this chemical packed and shipped?
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4-Fluoro-2-nitrophenyl isocyanate is carefully packed according to international regulations for hazardous chemicals and is available for global export by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or a sample of 4-Fluoro-2-nitrophenyl isocyanate, please contact our sales department through the website or direct email, providing your specific requirements.
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