1-(2-Furoyl)-1H-benzotriazole
1-(2-Furoyl)-1H-benzotriazole (CAS 144223-33-6) is a crystalline benzotriazole-based acylating reagent with the molecular formula C11H7N3O2 and a molar mass of 213.19 g/mol. In this N-acylbenzotriazole the benzotriazol-1-yl group acts as a stable yet readily displaced leaving group, making the reagent a convenient, controlled source of the 2-furoyl (furan-2-carbonyl) moiety in organic synthesis. Tech Serve Solutions supplies it as a research-grade reagent of 97% assay for C-C and C-heteroatom bond formation.
- Synonyms
- 1-(2-Furoyl)-1H-benzotriazole1-(Benzotriazol-1-yl)-2-furylmethanoneBenzotriazol-1-yl furan-2-yl ketone1-(2-Furylcarbonyl)benzotriazoleN-(2-Furoyl)benzotriazolefuran-2-yl(1H-benzotriazol-1-yl)methanone
Mild 2-furoyl acylating reagent
Serves as a bench-stable N-acylbenzotriazole that transfers the furan-2-carbonyl group to amines, alcohols and other nucleophiles under mild conditions, releasing benzotriazole as the leaving group. It offers a practical alternative to the corresponding acid chloride where milder, more selective acylation is preferred.
Amide and ester synthesis
Used to prepare furan-2-carboxamides and the related esters by reaction with amines or alcohols. The reagent is valued in medicinal and heterocyclic chemistry for introducing the furoyl unit cleanly without strongly activating or corrosive coupling agents.
C-C bond formation and synthetic building block
Acts as an acyl anion equivalent and acylating partner in carbon-carbon bond-forming reactions, consistent with its classification as a reagent for C-C bond formation and chemical synthesis. It is a useful building block for assembling more elaborate furan-containing scaffolds.
Research and laboratory reagent
Employed at laboratory and process-development scale as a controlled-release acyl donor in methodology studies and the preparation of intermediates. Its defined assay and reproducible solid form support consistent results across synthetic routes.
| Molecular weight | 213.19 |
|---|---|
| Empirical formula | C11H7N3O2 |
| Assay | 97% |
| Melting point | 165-169 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Furoyl)-1H-benzotriazole used for?
+
It is used as a mild, bench-stable acylating reagent that transfers the 2-furoyl (furan-2-carbonyl) group to amines, alcohols and other nucleophiles, with benzotriazole acting as the leaving group. This makes it a convenient reagent for preparing furan-2-carboxamides, esters and related intermediates, and for C-C bond formation in organic and medicinal chemistry.
What is the CAS number and molecular formula of 1-(2-Furoyl)-1H-benzotriazole?
+
The CAS number is 144223-33-6 and the molecular formula is C11H7N3O2, corresponding to a molecular weight of 213.19 g/mol. Its MDL number is MFCD00452996 and the reported melting point is 165-169 °C.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-(2-Furoyl)-1H-benzotriazole as a research/technical-grade reagent with a typical assay of 97%. We do not represent this material as USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch, and exact specifications can be confirmed against the current lot on request.
What are the safety and handling requirements for this reagent?
+
It is classified under GHS07 with the signal word Warning and the hazard statement H302 (harmful if swallowed). Handle in a well-ventilated area, avoid ingestion and dust formation, and use suitable personal protective equipment including an N95-type dust mask, eye protection and gloves. It carries German Water Hazard Class WGK 3 (severely hazardous to water), so prevent release into drains, soil and water. Always consult the Safety Data Sheet before use.
How is 1-(2-Furoyl)-1H-benzotriazole packed, shipped and exported?
+
The material is packed as a solid in tightly sealed containers appropriate to the order size, with full labelling and documentation. As a specialist exporter, Tech Serve Solutions arranges compliant international shipping with a certificate of analysis and Safety Data Sheet; packaging and transport details are confirmed at the time of order.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with the product name, CAS number 144223-33-6 and your required quantity, purity and destination. We will respond with availability, lead time, documentation and a formal quotation, and can arrange samples where appropriate.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
1-(2-Hydroxyethyl)-1H-1,2,3-triazole-4-carboxylic acid
Chemical Synthesis
