Ethyl (R)-(−)-mandelate
Ethyl (R)-(−)-mandelate (CAS: 10606-72-1) is a chiral ester with the formula C6H5CH(OH)CO2C2H5 and a molecular weight of 180.20 g/mol. This optically active compound, with a specific rotation of [α]21/D −134°, serves as a valuable chiral building block in asymmetric synthesis and general chemical synthesis. Its high optical purity (ee: 99%) makes it suitable for stereoselective reactions in organic chemistry.
Chiral Building Block in Asymmetric Synthesis
Ethyl (R)-(−)-mandelate is frequently employed as a chiral precursor for the construction of complex, stereochemically defined molecules. Its defined stereocenter allows for the introduction of chirality in target compounds.
Intermediate in Pharmaceutical Synthesis
This compound can function as an intermediate in the synthesis of active pharmaceutical ingredients (APIs) where specific stereochemistry is critical for biological activity. Its ester and alcohol functionalities offer versatile reaction pathways.
Reagent in Organic Synthesis
As an ester and a secondary alcohol, Ethyl (R)-(−)-mandelate participates in various organic transformations, including ester hydrolysis, transesterification, and oxidation reactions. Its chirality influences the stereochemical outcome of subsequent steps.
| Molecular weight | 180.20 |
|---|---|
| Linear formula | C6H5CH(OH)CO2C2H5 |
| Assay | 99% |
| Boiling point | 103-105 °C/2 mmHg(lit.) |
| Optical activity | [α]21/D −134°, c = 3 in chloroform |
| Optical purity | ee: 99% (GLC) |
| Melting point | 33-34 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (R)-(−)-mandelate used for?
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Ethyl (R)-(−)-mandelate is primarily used as a chiral building block in asymmetric synthesis and general chemical synthesis, and as an intermediate in pharmaceutical synthesis.
What are the CAS number and chemical formula for Ethyl (R)-(−)-mandelate?
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The CAS number is 10606-72-1 and the linear chemical formula is C6H5CH(OH)CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl (R)-(−)-mandelate with an assay of 99% and optical purity of ee: 99% (GLC). This is a technical/research grade and TSS does not represent it as USP, BP, or EP grade.
How should Ethyl (R)-(−)-mandelate be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. It has a flash point of >113 °C (>235.4 °F) and has a WGK rating of 3 in Germany, indicating a high hazard to water.
Is Ethyl (R)-(−)-mandelate a controlled substance?
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The provided data does not indicate that Ethyl (R)-(−)-mandelate is a controlled substance.
How is Ethyl (R)-(−)-mandelate packed, shipped, or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing, shipping, and export details are available upon request when placing an order or inquiry.
How can I request a sample or quote for Ethyl (R)-(−)-mandelate?
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You can request a sample or a quote by contacting the Tech Serve Solutions sales department through the website or by calling our main office.
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