Ethyl (R)-1-Boc-4-oxopiperidine-2-carboxylate
Ethyl (R)-1-Boc-4-oxopiperidine-2-carboxylate (CAS: 357154-16-6, C13H21NO5) is a valuable chiral building block with a molecular weight of 271.31 g/mol. This Boc-protected piperidine derivative features a ketone functionality, making it a versatile intermediate in asymmetric synthesis and complex molecule construction. Its specific stereochemistry and functional groups enable its use in creating intricate heterocyclic structures relevant to pharmaceutical research and development.
- IUPAC
- (R)-1-Boc-4-oxopiperidine-2-carboxylic acid ethyl ester

Chiral Building Block
Utilised as a key stereodefined intermediate in the synthesis of complex chiral molecules. Its defined (R)-configuration is crucial for establishing specific stereocentres in target compounds.
Asymmetric Synthesis
Employed in asymmetric synthetic routes to construct enantiomerically pure or enriched compounds. The compound's inherent chirality can direct the stereochemical outcome of subsequent reactions.
Heterocyclic Chemistry
Serves as a precursor for the synthesis of various substituted piperidine and related heterocyclic systems. These motifs are frequently found in biologically active molecules.
Pharmaceutical Intermediate
A valuable intermediate in the development of novel pharmaceutical agents. Its structure allows for diverse functionalization to explore structure-activity relationships.
| Molecular weight | 271.31 |
|---|---|
| Empirical formula | C13H21NO5 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 42-47 °C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (R)-1-Boc-4-oxopiperidine-2-carboxylate used for?
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Ethyl (R)-1-Boc-4-oxopiperidine-2-carboxylate is primarily used as a chiral building block in asymmetric synthesis and for the construction of complex heterocyclic molecules, particularly in pharmaceutical research and development.
What are the CAS number and formula for Ethyl (R)-1-Boc-4-oxopiperidine-2-carboxylate?
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The CAS number is 357154-16-6, and the molecular formula is C13H21NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should Ethyl (R)-1-Boc-4-oxopiperidine-2-carboxylate be handled?
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This compound is classified as a Warning, causing serious eye irritation (H319). When handling, wear protective gloves and eye protection, and if in eyes, rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Ensure good ventilation.
How is this chemical shipped or exported?
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As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping and customs regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or obtain a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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