Ethyl (R)-N-Boc-piperidine-3-carboxylate
Ethyl (R)-N-Boc-piperidine-3-carboxylate (CAS: 194726-40-4; Formula: C13H23NO4; MW: 257.33) is a chiral heterocyclic building block used in chemical synthesis. Supplied by Tech Serve Solutions (TSS) with an assay of 95%, this compound is a valuable intermediate in asymmetric synthesis. Its piperidine core, functionalised with a Boc-protected amine and an ethyl ester, makes it suitable for constructing complex molecular architectures.
- IUPAC
- (R)-(−)-N-Boc-nipecotic acid ethyl ester,(R)-1-(tert-Butoxycarbonyl)-piperidine-3-carboxylic acid ethyl ester,(R)-1-(tert-Butyl) 3-ethyl 1,3-piperidinedicarboxylate,Ethyl (3R)-1-tert-butoxycarbonyl-3-piperidinecarboxylate
- Synonyms
- (R)-1-(tert-Butoxycarbonyl)-piperidine-3-carboxylic acid ethyl ester(R)-1-tert-Butoxycarbonyl-3-piperidinecarboxylic acid ethyl ester(R)-(-)-N-Boc-nipecotic acid ethyl ester(R)-1-(tert-Butyl) 3-ethyl 1,3-piperidinedicarboxylateEthyl (3R)-1-tert-butoxycarbonyl-3-piperidinecarboxylate
Chiral Building Block in Asymmetric Synthesis
This enantiomerically pure piperidine derivative serves as a key chiral building block. It is instrumental in the stereoselective synthesis of complex organic molecules, particularly in pharmaceutical research and development where specific enantiomers are often required for biological activity.
Intermediate for Heterocyclic Compound Synthesis
The compound's piperidine ring structure makes it an ideal precursor for synthesising a variety of nitrogen-containing heterocyclic compounds. These structures are prevalent in many biologically active molecules and natural products.
Research and Development in Organic Chemistry
Utilised in academic and industrial research labs for the development of novel synthetic methodologies and the creation of new chemical entities. Its well-defined stereochemistry facilitates predictable outcomes in multi-step syntheses.
| Molecular weight | 257.33 |
|---|---|
| Empirical formula | C13H23NO4 |
| Assay | 95% |
| Melting point | 36-40 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (R)-N-Boc-piperidine-3-carboxylate primarily used for?
+
Ethyl (R)-N-Boc-piperidine-3-carboxylate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate for creating complex heterocyclic compounds, particularly in pharmaceutical research and development.
What are the CAS number and chemical formula for this compound?
+
The CAS number is 194726-40-4, and the chemical formula is C13H23NO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Ethyl (R)-N-Boc-piperidine-3-carboxylate with a minimum assay of 95%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
+
This compound is classified as harmful if swallowed and causes skin, eye, and respiratory irritation (H302-H315-H319-H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Ensure good ventilation and avoid breathing dust.
How is this product packed and exported by TSS?
+
Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for safe transport and export according to international regulations. Please contact us for specific shipping and export details.
How can I request a sample or quote for this product?
+
To request a sample or a quote, please contact our sales department through the TSS website or by direct inquiry. Our team will be pleased to assist you with your requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis