Ethyl (R)-(−)-3-hydroxybutyrate
Ethyl (R)-(−)-3-hydroxybutyrate (CAS: 24915-95-5), with the linear formula CH3CH(OH)CH2CO2C2H5 and a molecular weight of 132.16 g/mol, is a chiral ester vital in asymmetric synthesis. It serves as a valuable building block for creating complex organic molecules, particularly in pharmaceutical and fine chemical research and development. Its defined stereochemistry makes it an important intermediate for stereoselective reactions.

Chiral Building Block in Organic Synthesis
Utilised as a fundamental chiral synthon for the stereoselective construction of more complex molecules. Its hydroxyl and ester functionalities allow for diverse chemical transformations.
Pharmaceutical Intermediate Development
A key intermediate in the synthesis of chiral active pharmaceutical ingredients (APIs). Its enantiopure nature is crucial for developing drugs with specific biological activities and reduced side effects.
Asymmetric Synthesis Research
Employed in academic and industrial research settings to explore novel asymmetric synthetic routes and methodologies. It aids in the development of stereospecific catalytic processes.
Fine Chemical Manufacturing
Serves as a precursor in the production of various fine chemicals where precise stereochemistry is a requirement for product performance and efficacy.
| Molecular weight | 132.16 |
|---|---|
| Linear formula | CH3CH(OH)CH2CO2C2H5 |
| Assay | 98% |
| Boiling point | 75-76 °C/12 mmHg(lit.) |
| Density | 1.017 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.42(lit.) |
| Optical activity | [α]20/D −46°, c = 1 in chloroform |
| Optical purity | ee: 99% (GLC) |
| Flash point | 64 °C / 147.2 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 52 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (R)-(−)-3-hydroxybutyrate primarily used for?
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Ethyl (R)-(−)-3-hydroxybutyrate is primarily used as a chiral building block in asymmetric synthesis, particularly in the development of pharmaceutical intermediates and fine chemicals where stereospecificity is essential.
What is the CAS number and chemical formula for Ethyl (R)-(−)-3-hydroxybutyrate?
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The CAS number is 24915-95-5, and the linear chemical formula is CH3CH(OH)CH2CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl (R)-(−)-3-hydroxybutyrate with an assay of 98%. This is a technical or research grade material, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethyl (R)-(−)-3-hydroxybutyrate be handled safely?
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Ethyl (R)-(−)-3-hydroxybutyrate is combustible with a flash point of 64 °C (147.2 °F). It is classified under WGK 2 in Germany, indicating it is hazardous to water. Standard laboratory safety precautions should be observed, including working in a well-ventilated area and avoiding ignition sources.
Is Ethyl (R)-(−)-3-hydroxybutyrate shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Ethyl (R)-(−)-3-hydroxybutyrate, and can arrange for international shipment.
How can I request a quote or sample for Ethyl (R)-(−)-3-hydroxybutyrate?
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To request a quote or a sample of Ethyl (R)-(−)-3-hydroxybutyrate, please contact our sales team through the website or by phone, providing your specific requirements.
What is the optical activity of this compound?
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The optical activity is specified as [α]20/D −46°, c = 1 in chloroform, with an optical purity (ee) of 99% determined by GLC.
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