Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate (CAS: 90866-33-4) is a chiral ester and organic building block crucial for asymmetric synthesis. With a molecular weight of 166.60 g/mol, this compound serves as a versatile intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and fine chemical research and development. Its defined stereochemistry makes it valuable for stereoselective reactions, enabling the creation of specific enantiomers required for biologically active compounds.
Chiral Building Block in Organic Synthesis
Serves as a key chiral synthon for constructing enantiomerically pure compounds. Its defined (R)-configuration is essential for stereoselective synthesis pathways, particularly in the development of pharmaceuticals and agrochemicals where specific stereoisomers are required for efficacy and safety.
Intermediate for Pharmaceutical Synthesis
Utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its functional groups allow for diverse chemical transformations, making it adaptable for creating complex molecular architectures found in various therapeutic agents.
Reagent in Asymmetric Catalysis Research
Employed in academic and industrial research focused on developing new asymmetric methodologies. It acts as a substrate or precursor to study and optimise stereoselective transformations, contributing to advancements in chiral chemistry.
| Molecular weight | 166.60 |
|---|---|
| Linear formula | ClCH2CH(OH)CH2CO2C2H5 |
| Assay | 96% |
| Boiling point | 93-95 °C/5 mmHg(lit.) |
| Density | 1.19 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.453(lit.) |
| Optical activity | [α]23/D +14°, neat |
| Optical purity | ee: 97% (GLC) |
Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate used for?
+
Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is primarily used as a chiral building block in organic synthesis, particularly for the development of pharmaceuticals and fine chemicals where precise stereochemistry is required.
What is the CAS number and chemical formula for Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate?
+
The CAS number is 90866-33-4, and its linear formula is ClCH₂CH(OH)CH₂CO₂C₂H₅.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate with an assay of 96% and an optical purity of ee: 97% (GLC). This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate be handled safely?
+
This compound is classified as Danger (GHS05) and causes serious eye damage (H318). Appropriate personal protective equipment, including eyeshields and gloves, must be worn. Handle with adequate ventilation and consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
How is Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate packed, shipped, and exported?
+
Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant transportation and regulatory requirements to ensure safe and compliant delivery worldwide.
How can I request a sample or quote for Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate?
+
To request a sample or a quotation, please contact our sales team through the website or by phone. Provide the product name and CAS number (90866-33-4) for prompt service.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis