1-(2-Fluorophenyl)piperazine monohydrochloride
1-(2-Fluorophenyl)piperazine monohydrochloride (CAS 1011-16-1) is a fluorinated arylpiperazine supplied as the monohydrochloride salt, with the empirical formula C10H13FN2 · HCl and a molecular weight of 216.68. It is a heterocyclic building block used in chemical synthesis and medicinal-chemistry research, where its ortho-fluorinated phenylpiperazine scaffold serves as an intermediate for the preparation of more complex molecules. Tech Serve Solutions supplies it as a research-grade reagent at 98% assay.
- Synonyms
- 1-(2-Fluorophenyl)piperazine monohydrochloride1-(2-Fluorophenyl)piperazine hydrochloride2-Fluorophenylpiperazine hydrochloride1-(2-Fluorophenyl)piperazine HClo-Fluorophenylpiperazine hydrochloride
Heterocyclic building block
Serves as a piperazine building block in chemical synthesis, providing a pre-formed ortho-fluorinated phenylpiperazine ring system that can be elaborated further. The secondary piperazine nitrogen offers a convenient handle for alkylation, acylation and related functionalisation.
Pharmaceutical and medicinal-chemistry intermediate
Arylpiperazines are a recurring motif in medicinal chemistry, and this fluorinated example is used as an intermediate in research programmes and structure-activity studies. It is supplied for research and manufacturing use, not for clinical or therapeutic application.
Fluorinated scaffold for analogue synthesis
The ortho-fluorine substituent on the aromatic ring makes the compound useful for preparing fluorinated analogues and exploring the effect of fluorine substitution on a phenylpiperazine core.
Laboratory reagent
Used as a defined research-grade reagent in synthetic and discovery laboratories. The hydrochloride salt form aids handling, weighing and storage relative to the free base.
| Molecular weight | 216.68 |
|---|---|
| Empirical formula | C10H13FN2 · HCl |
| Assay | 98% |
| Melting point | 187-189 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Fluorophenyl)piperazine monohydrochloride used for?
+
It is used principally as a heterocyclic building block and synthetic intermediate. The fluorinated phenylpiperazine scaffold is employed in chemical synthesis and medicinal-chemistry research to build more complex molecules and fluorinated analogues. It is supplied for research and manufacturing use only.
What is the CAS number and molecular formula of 1-(2-Fluorophenyl)piperazine monohydrochloride?
+
The CAS number is 1011-16-1. The empirical formula is C10H13FN2 · HCl (the monohydrochloride salt), with a molecular weight of 216.68. Its MDL number is MFCD00134409 and the PubChem substance ID is 24863380.
What grade and purity does Tech Serve Solutions supply?
+
We supply 1-(2-Fluorophenyl)piperazine monohydrochloride as a research/technical-grade reagent at 98% assay, with a reported melting point of 187-189 °C. We do not represent this material as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements for this compound?
+
It is classified under GHS07 with the signal word Warning and hazard statements H302, H312, H315, H319, H332 and H335 — harmful if swallowed, in contact with skin or if inhaled, and causing skin, eye and respiratory irritation. Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and consult the Safety Data Sheet before use. It carries water-hazard class WGK 3 (Germany), so spillage to water must be prevented.
How is 1-(2-Fluorophenyl)piperazine monohydrochloride packed, shipped and exported?
+
The product is packed in sealed, appropriately labelled containers sized to the order, from gram quantities to bulk, with packaging and documentation prepared to meet applicable transport and export regulations. As a long-standing global supplier and exporter, Tech Serve Solutions arranges international shipment with the required GHS labelling and Safety Data Sheet.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will confirm availability, lead time and documentation. We can provide a certificate of analysis and Safety Data Sheet, and discuss sample or bulk requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
1-(2-Hydroxyethyl)-1H-1,2,3-triazole-4-carboxylic acid
Chemical Synthesis
