1-(2-Fluorophenyl)biguanide hydrochloride
1-(2-Fluorophenyl)biguanide hydrochloride (CAS 66088-51-5) is an aryl-substituted biguanide salt with the linear formula FC6H4NHC=NHNHC=NHNH2 · HCl and a molecular weight of 231.66. Supplied as a research-grade solid of about 97% assay, it serves chiefly as an organic building block and guanidine reagent in chemical synthesis, where its nitrogen-rich biguanide core supports the construction of triazines and related heterocyclic intermediates.
- Synonyms
- 1-(2-Fluorophenyl)biguanide hydrochlorideN-(2-Fluorophenyl)imidodicarbonimidic diamide hydrochloride2-Fluorophenyl biguanide hydrochloride1-(2-Fluorophenyl)biguanide HClCAS 66088-51-5MFCD00236682
Guanidine building block for synthesis
Used as a nitrogen-rich biguanide reagent in multistep organic synthesis. The 2-fluorophenyl substituent and reactive biguanide chain make it a versatile intermediate for assembling more complex molecules.
Heterocycle and triazine construction
Biguanides of this type are widely employed to build 1,3,5-triazine and other N-heterocyclic ring systems through cyclisation chemistry. It provides a defined aryl-biguanide scaffold for such ring-forming reactions.
Pharmaceutical and fine-chemical intermediates
As a guanidine-class organic building block, it is suited to the preparation of intermediates in pharmaceutical and fine-chemical research programmes. Specific downstream applications depend on the customer's chosen route.
Laboratory research and discovery
Supplied as a research-grade reagent for laboratory-scale exploration and structure-activity studies. The fluorinated aromatic ring is a common motif for tuning the properties of candidate compounds.
| Molecular weight | 231.66 |
|---|---|
| Linear formula | FC6H4NHC=NHNHC=NHNH2 · HCl |
| Assay | 97% |
| Melting point | 237-241 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Fluorophenyl)biguanide hydrochloride used for?
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It is used mainly as an organic building block and guanidine reagent in chemical synthesis. Its nitrogen-rich biguanide core is particularly useful for constructing 1,3,5-triazines and other heterocyclic intermediates in pharmaceutical and fine-chemical research.
What is the CAS number and molecular formula of 1-(2-Fluorophenyl)biguanide hydrochloride?
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The CAS number is 66088-51-5 and the linear formula is FC6H4NHC=NHNHC=NHNH2 · HCl, corresponding to the 2-fluorophenyl biguanide free base as its hydrochloride salt. The molecular weight is 231.66 and the MDL number is MFCD00236682.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research/technical-grade solid with an assay of approximately 97%. We do not represent it as USP, BP or EP pharmacopoeial grade. A specification or certificate of analysis can be provided with each batch on request.
What safety and handling precautions apply?
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Handle the material with appropriate personal protective equipment, including eye protection, gloves and a suitable particulate respirator (type N95 / P1). It is classified as a severe hazard to water (WGK Germany 3), so prevent release to drains and watercourses. Always consult the current Safety Data Sheet for the full GHS classification before use.
How is 1-(2-Fluorophenyl)biguanide hydrochloride packed, shipped and exported?
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It is packed as a dry solid in sealed, clearly labelled containers sized to the order, from gram quantities upward, with documentation suited to laboratory and research use. Tech Serve Solutions arranges compliant export shipping and supporting paperwork to destinations worldwide.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and delivery destination, and our team will respond with availability, lead time and a formal quotation. Sample requests for evaluation can be accommodated where appropriate.
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