Tyrphostin AG 825
Tyrphostin AG 825 (CAS: 149092-50-2) is a potent inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. With the molecular formula C19H15N3O3S2 and a molecular weight of 397.47 g/mol, this bioactive small molecule is supplied by Tech Serve Solutions for research applications. It plays a significant role in cell signaling studies, particularly concerning cell proliferation and differentiation, by blocking key intracellular signaling pathways mediated by receptor tyrosine kinases.
- IUPAC
- 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide,Tyrphostin C15
- Synonyms
- Tyrphostin C15
EGFR Tyrosine Kinase Inhibition
Tyrphostin AG 825 serves as a research tool to investigate the role of Epidermal Growth Factor Receptor (EGFR) tyrosine kinase in cellular processes. Its inhibitory action allows researchers to study downstream signaling pathways affected by EGFR activation.
Cell Signaling Pathway Research
This compound is utilised in studies examining cell signaling and neuroscience, where blocking tyrosine kinase activity is crucial for understanding signal transduction. It helps elucidate mechanisms involved in cell growth, differentiation, and survival.
Biochemical Research Tool
As a biochemical reagent, Tyrphostin AG 825 is employed in laboratory settings to probe enzymatic functions. Its specific inhibition of tyrosine kinases makes it valuable for enzyme assays and for studying kinase-mediated biological responses.
Iodide Uptake Studies
Tyrphostin AG 825 has been used experimentally to investigate its impact on iodide uptake in specific cell lines, such as EMT6 cells, contributing to the understanding of cellular transport mechanisms influenced by kinase signalling.
| Molecular weight | 397.47 |
|---|---|
| Empirical formula | C19H15N3O3S2 |
| Assay | ≥92.5% |
| Solubility | DMSO: solublemethanol: soluble |
| Storage temperature | −20°C |
| Application | Tyrphostin AG 825 has been used to study its effects on iodide uptake in EMT6 cells1. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tyrphostin AG 825 used for?
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Tyrphostin AG 825 is primarily used as a research tool to inhibit Epidermal Growth Factor Receptor (EGFR) tyrosine kinase, facilitating studies in cell signaling, kinase biology, and cellular processes such as iodide uptake.
What are the CAS number and molecular formula for Tyrphostin AG 825?
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The CAS number for Tyrphostin AG 825 is 149092-50-2, and its molecular formula is C19H15N3O3S2.
What grade and purity does Tech Serve Solutions supply for Tyrphostin AG 825?
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Tech Serve Solutions supplies Tyrphostin AG 825 with a minimum purity of 92.5% (Assay: ≥92.5%). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Tyrphostin AG 825 be handled and stored?
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Handle Tyrphostin AG 825 with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the compound at -20°C.
Is Tyrphostin AG 825 a controlled substance?
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The provided data does not indicate that Tyrphostin AG 825 is a controlled substance.
How is Tyrphostin AG 825 shipped and exported?
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Tech Serve Solutions, a global supplier and exporter of fine chemicals, ships and exports Tyrphostin AG 825 according to international regulations for chemical transport. Specific shipping details can be provided upon request.
How can I request a quote or sample for Tyrphostin AG 825?
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To request a quote or a sample of Tyrphostin AG 825, please contact our sales department through the website or by phone, providing your specific requirements.
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