U-62066
U-62066 (CAS: 87151-85-7), a kappa opioid receptor agonist, presents as a white solid with the molecular formula C22H30Cl2N2O2 · CH3SO3H and a molecular weight of 521.50. This compound is primarily utilised in neurobiological and cell signalling research as a pharmacological tool. Its solubility in water is approximately 14 mg/mL, while it is insoluble in methanol. U-62066 is stored under refrigerated conditions (2-8°C).
- IUPAC
- (±)-(5α,7α,8β)-3,4-Dichloro-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide mesylate salt,Spiradoline mesylate salt
- Synonyms
- (±)-(5α,7α,8β)-3,4-Dichloro-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide mesylate salt,Spiradoline mesylate salt

Neuroscience Research
U-62066 serves as a selective kappa opioid receptor agonist. It is instrumental in investigating the roles of kappa opioid receptors in pain perception, mood regulation, and other neurological processes.
Cell Signalling Studies
This compound is employed to study intracellular signalling pathways modulated by kappa opioid receptor activation. It aids in understanding the downstream effects of receptor binding in cellular models.
Pharmacological Tool
As a well-defined opioid agonist, U-62066 is valuable for in vitro and in vivo studies aimed at characterising opioid receptor function and developing novel therapeutics.
| Molecular weight | 521.50 |
|---|---|
| Linear formula | C22H30Cl2N2O2 · CH3SO3H |
| Form | solid |
| Colour | white |
| Solubility | H2O: soluble14 mg/mLmethanol: insoluble |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... OPRK1(4986) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is U-62066 used for?
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U-62066 is used as a research tool in neuroscience and cell signalling, specifically as a selective kappa opioid receptor agonist for studying neurological processes and opioid receptor function.
What is the CAS number and molecular formula for U-62066?
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The CAS number for U-62066 is 87151-85-7, and its molecular formula is C22H30Cl2N2O2 · CH3SO3H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies U-62066 in a form suitable for research purposes. The specific assay and purity are detailed in the product specifications. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should U-62066 be handled and stored?
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U-62066 is a solid and requires handling with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It should be stored at 2-8°C.
Is U-62066 a controlled substance?
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Based on the provided data, U-62066 is classified under WGK Germany 3. It is not explicitly listed as a controlled substance in the provided safety information.
How are products from Tech Serve Solutions packed and shipped?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents, ensuring appropriate packaging and adherence to shipping regulations for all products.
How can I request a sample or quote for U-62066?
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To request a sample or obtain a quote for U-62066, please contact the Tech Serve Solutions sales team through the official website or designated contact channels.
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