Tyrphostin AG 1296

CAS 146535-11-7C16H14N2O2Biochemicals & Reagents

Tyrphostin AG 1296 (CAS: 146535-11-7; Formula: C16H14N2O2; MW: 266.29 g/mol) is a potent inhibitor of receptor tyrosine kinases (RTKs), particularly the Platelet-Derived Growth Factor Receptor (PDGFR). This bioactive small molecule is widely used in research for its ability to block RTK signalling pathways. Available from Tech Serve Solutions with an assay of ≥98%, it serves as a valuable reagent in cell biology and kinase signalling studies.

IUPAC: 6,7-Dimethoxy-2-phenylquinoxaline
Synonyms: 6,7-Dimethoxy-2-phenylquinoxaline

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Tyrphostin AG 1296 (C16H14N2O2) — chemical structure, CAS 146535-11-7; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand SubstratesKinase/Phosphatase BiologyP to Q

01 /Applications

Inhibition of PDGFR Signalling

Tyrphostin AG 1296 is employed to specifically inhibit the activity of Platelet-Derived Growth Factor Receptor (PDGFR) kinases. This allows researchers to investigate the downstream effects of PDGFR signalling in cellular processes.

Cellular Signalling Research

As a selective inhibitor of certain tyrosine kinases, it is used to study signal transduction pathways, cell proliferation, and differentiation regulated by RTKs in various cell types.

Biochemical Research Reagent

This compound serves as a critical research tool for understanding enzyme function and developing new therapeutic strategies targeting kinase-dependent pathways.

02 /Properties

Molecular weight	266.29
Empirical formula	C16H14N2O2
Assay	≥98%
Solubility	methylene chloride: soluble10 mg/mLDMSO: soluble
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

146535-11-7

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tyrphostin AG 1296 used for?

Tyrphostin AG 1296 is primarily used as a research chemical to inhibit receptor tyrosine kinases, particularly PDGFR, and to study cellular signalling pathways.

What are the CAS number and formula for Tyrphostin AG 1296?

The CAS number for Tyrphostin AG 1296 is 146535-11-7, and its molecular formula is C16H14N2O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tyrphostin AG 1296 with a minimum purity of 98% (Assay: ≥98%). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should Tyrphostin AG 1296 be handled and stored?

Handle Tyrphostin AG 1296 with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the compound at 2-8°C.

Is Tyrphostin AG 1296 a controlled substance?

The provided data does not indicate that Tyrphostin AG 1296 is a controlled substance. However, users should always verify local regulations.

How is Tyrphostin AG 1296 packed and exported?

Tyrphostin AG 1296 is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions, adhering to international shipping regulations for chemicals.