(Trimethylphosphoranylidene)acetonitrile solution
(Trimethylphosphoranylidene)acetonitrile solution, CAS 176325-83-0 (C5H10NP), is a valuable reagent with a molecular weight of 115.11 g/mol. Supplied as a 0.5 M solution in THF, it is primarily utilised in chemical synthesis for C-X bond formation and is particularly noted for its role in Mitsunobu reactions. Its properties make it a key component in advanced organic synthesis workflows.
- IUPAC
- CMMP,Cyanomethylenetrimethylphosphorane solution
- Synonyms
- CMMP,Cyanomethylenetrimethylphosphorane solution
C-X Bond Formation
This reagent is effectively employed in the formation of carbon-heteroatom bonds, facilitating crucial transformations in organic synthesis. Its application is well-documented in the construction of complex molecular architectures.
Mitsunobu Reaction Reagent
As a key component in the Mitsunobu reaction, it enables the stereospecific inversion of alcohols, a vital process for the synthesis of chiral molecules. This application is fundamental in pharmaceutical and fine chemical production.
Chemical Synthesis
The compound serves as a versatile building block and reagent in various organic synthesis pathways. Its unique reactivity profile allows for diverse synthetic strategies in academic and industrial research.
| Molecular weight | 115.11 |
|---|---|
| Empirical formula | C5H10NP |
| Density | 0.896 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -21 °C / -5.8 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-22-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trimethylphosphoranylidene)acetonitrile solution used for?
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(Trimethylphosphoranylidene)acetonitrile solution is used in chemical synthesis, particularly for C-X bond formation and in Mitsunobu reactions.
What are the CAS number and formula for (Trimethylphosphoranylidene)acetonitrile solution?
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The CAS number is 176325-83-0 and the empirical formula is C5H10NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not claim USP, BP, or EP grade unless explicitly stated in the product specifications. For specific purity requirements, please consult the product data sheet.
How should (Trimethylphosphoranylidene)acetonitrile solution be handled?
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This solution is a flammable liquid and vapour, harmful if swallowed or inhaled, and causes serious eye irritation. It may also cause respiratory irritation and is suspected of causing cancer. Handle with appropriate personal protective equipment in a well-ventilated area. May form explosive peroxides. Store at 2-8°C, away from ignition sources.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and reagents, including (Trimethylphosphoranylidene)acetonitrile solution.
How can I request a sample or quote?
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Please contact our sales team through the website to request a sample or a quotation for (Trimethylphosphoranylidene)acetonitrile solution.
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