(Triisopropylsilyl)acetylene
(Triisopropylsilyl)acetylene (CAS: 89343-06-6, C9H20Si) is a terminal alkyne featuring a bulky triisopropylsilyl protecting group. This compound is valuable in organic synthesis as a building block, offering a protected ethynyl functionality for subsequent reactions. Its steric bulk can influence regioselectivity and stereoselectivity in synthetic pathways. It is commonly employed in the construction of complex organic molecules and in materials science research.
- IUPAC
- Ethynyltriisopropylsilane
- Synonyms
- Ethynyltriisopropylsilane
![(Triisopropylsilyl)acetylene ([(CH3)2CH]3SiC≡CH) — chemical structure, CAS 89343-06-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F89343-06-6.png&w=3840&q=75)
Organic Synthesis Building Block
Serves as a versatile intermediate in organic chemistry. The triisopropylsilyl group provides protection for the terminal alkyne, allowing for selective functionalization elsewhere in a molecule before deprotection and further alkyne chemistry.
Protecting Group Chemistry
The bulky triisopropylsilyl (TIPS) moiety effectively shields the acetylenic proton, facilitating reactions that might otherwise occur at this position. This allows for controlled elaboration of synthetic targets.
Materials Science
Incorporated into the synthesis of novel polymers and advanced materials where precise control over alkyne incorporation is required for tuning material properties.
| Molecular weight | 182.38 |
|---|---|
| Linear formula | [(CH3)2CH]3SiC≡CH |
| Assay | ≥98.0% (GC) |
| Boiling point | 50-52 °C/0.6 mmHg(lit.) |
| Density | 0.813 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4527(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 56 °C / 132.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Triisopropylsilyl)acetylene used for?
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(Triisopropylsilyl)acetylene is primarily used as a building block in organic synthesis, serving to introduce a protected ethynyl group into molecules. Its bulky silyl protecting group allows for selective chemical transformations.
What is the CAS number and formula for (Triisopropylsilyl)acetylene?
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The CAS number for (Triisopropylsilyl)acetylene is 89343-06-6, and its molecular formula is C9H20Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Triisopropylsilyl)acetylene with a purity of ≥98.0% as determined by GC. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (Triisopropylsilyl)acetylene be handled safely?
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(Triisopropylsilyl)acetylene is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
Is (Triisopropylsilyl)acetylene a controlled substance?
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The provided data does not indicate that (Triisopropylsilyl)acetylene is a controlled substance.
How is (Triisopropylsilyl)acetylene shipped and exported?
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As a chemical supplier, Tech Serve Solutions adheres to all relevant transportation and export regulations for chemicals, including those for flammable liquids like (Triisopropylsilyl)acetylene (UN 1993).
How can I request a quote or sample of (Triisopropylsilyl)acetylene?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (89343-06-6).
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