(Trifluoromethoxy)benzene
(Trifluoromethoxy)benzene, CAS 456-55-3, with the chemical formula C6H5OCF3 and a molecular weight of 162.11 g/mol, is a valuable organic building block. This ether derivative is primarily utilised in chemical synthesis, contributing to the creation of more complex organic molecules. Its distinct chemical properties make it an essential reagent for researchers and industrial chemists involved in organic synthesis and materials science.
- IUPAC
- α,α,α-Trifluoroanisole,Phenyl trifluoromethyl ether
- Synonyms
- α,α,α-TrifluoroanisolePhenyl trifluoromethyl ether
Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of diverse organic compounds. Its trifluoromethoxy group can be incorporated into target molecules to modify electronic and lipophilic properties.
Pharmaceutical Research
Used in the development of new pharmaceutical agents, where the trifluoromethoxy moiety can enhance metabolic stability or receptor binding affinity of drug candidates.
Materials Science
Incorporated into the design of novel materials, potentially impacting properties such as thermal stability or optical characteristics due to the presence of the fluorine atoms.
| Molecular weight | 162.11 |
|---|---|
| Linear formula | C6H5OCF3 |
| Assay | 99% |
| Boiling point | 102 °C(lit.) |
| Density | 1.226 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.406(lit.) |
| Vapour pressure | 41.3 mmHg (25 °C) |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 12 °C / 53.6 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trifluoromethoxy)benzene used for?
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(Trifluoromethoxy)benzene is primarily used as a building block and intermediate in organic synthesis, finding applications in pharmaceutical research and materials science.
What is the CAS number and chemical formula for (Trifluoromethoxy)benzene?
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The CAS number is 456-55-3 and the chemical formula is C6H5OCF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Trifluoromethoxy)benzene with an assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should (Trifluoromethoxy)benzene be handled safely?
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(Trifluoromethoxy)benzene is a flammable liquid and vapour (H225), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eye protection, gloves, and respiratory protection in a well-ventilated area. Keep away from heat, sparks, and open flames.
How is (Trifluoromethoxy)benzene packed, shipped, and exported?
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(Trifluoromethoxy)benzene is packed in accordance with safety regulations for flammable liquids and exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for (Trifluoromethoxy)benzene?
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To request a sample or quote for (Trifluoromethoxy)benzene, please contact our sales team through the website or by phone, providing your specific requirements.
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