(Trimethylsilyl)diazomethane solution
(Trimethylsilyl)diazomethane solution (CAS 18107-18-1), molecular formula (CH3)3SiCHN2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- (Diazomethyl)trimethylsilane
| Molecular weight | 114.22 |
|---|---|
| Linear formula | (CH3)3SiCHN2 |
| Density | 0.718 g/mL at 25 °C |
| Concentration | 2.0 M in hexanes |
| Application | Reactant for preparation of:• Macrolactam analogs of the natural product macrolide (-)-A26771B with improved metabolic stability and antibacterial activity1• Aigialomycin D analogues as protein kinase inhibitors for cancer treatment2• Unnatural α-amino acid derivatives containing gem-bisphosphonates via Michael addition reaction3• Capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates4• Stictamides A-C as matrix metallopeptidase 12 (MMP12) inhibitors with antitumor invasion activity5• Endothelin converting enzyme (ECE) Inhibitors WS 75624A and WS 75624B via a cross-metathesis approach6• Ent-kaurene derivatives as anti-inflammatory agents7• Desmosdumotin C analogs as potent antitumor agents acting via activation of spindle assembly checkpo |
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -23 °C / -9.4 °F |
| Transport (UN / ADR) | UN 3383 6.1(3) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T+,N |
| Risk statements (R) | 45-11-26-38-39/26-51/53-62-65-67 |
| Safety statements (S) | 53-28-36/37-45-61-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trimethylsilyl)diazomethane solution?
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(Trimethylsilyl)diazomethane solution (CAS 18107-18-1), molecular formula (CH3)3SiCHN2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of (Trimethylsilyl)diazomethane solution does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Trimethylsilyl)diazomethane solution in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of (Trimethylsilyl)diazomethane solution?
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(Trimethylsilyl)diazomethane solution has CAS number 18107-18-1 and molecular formula (CH3)3SiCHN2. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for (Trimethylsilyl)diazomethane solution?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of (Trimethylsilyl)diazomethane solution ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should (Trimethylsilyl)diazomethane solution be stored?
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Store (Trimethylsilyl)diazomethane solution in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is (Trimethylsilyl)diazomethane solution used for?
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(Trimethylsilyl)diazomethane solution is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for (Trimethylsilyl)diazomethane solution?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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