tert-Butyldimethylsilyl (S)-(+)-glycidyl ether
tert-Butyldimethylsilyl (S)-(+)-glycidyl ether (CAS: 123237-62-7, Formula: C9H20O2Si) is a chiral epoxide building block. With a molecular weight of 188.34 g/mol, this optically active compound serves as a valuable intermediate in asymmetric synthesis. Its defined stereochemistry makes it suitable for constructing complex chiral molecules, particularly in pharmaceutical research and development and fine chemical synthesis.
Chiral Building Block
Utilised as a key component in the synthesis of enantiomerically pure compounds. Its epoxide ring can be opened stereoselectively to introduce specific functional groups.
Asymmetric Synthesis
Serves as a versatile reagent for introducing chirality into organic molecules. It is instrumental in creating stereocenters required for biologically active compounds.
Pharmaceutical Intermediates
Acts as a precursor in the development of active pharmaceutical ingredients (APIs). Its structure allows for the facile construction of complex drug scaffolds.
Organic Synthesis
A useful reagent in general organic synthesis for creating functionalized chiral molecules. It enables the formation of carbon-carbon and carbon-heteroatom bonds with controlled stereochemistry.
| Molecular weight | 188.34 |
|---|---|
| Empirical formula | C9H20O2Si |
| Assay | 98% |
| Boiling point | 197-199 °C/760 mmHg |
| Density | 0.890 g/mL at 25 °C |
| Refractive index | n20/D 1.4320 |
| Optical activity | [α]22/D +6.5°, neat |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 73 °C / 163.4 °F |
| Transport (UN / ADR) | UN 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is tert-Butyldimethylsilyl (S)-(+)-glycidyl ether used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, particularly in the development of pharmaceutical intermediates and other complex organic molecules requiring specific stereochemistry.
What is the CAS number and formula?
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The CAS number is 123237-62-7 and the empirical formula (Hill notation) is C9H20O2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 98%. It is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should tert-Butyldimethylsilyl (S)-(+)-glycidyl ether be handled safely?
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This compound is classified with a GHS07 symbol and a Warning signal word. It carries hazard statements H302 (Harmful if swallowed) and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be worn. Ensure good ventilation. Store at 2-8°C.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including tert-Butyldimethylsilyl (S)-(+)-glycidyl ether.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team through the website or by phone. Please specify the quantity and intended use.
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