tert-Butyldimethylsilanol
tert-Butyldimethylsilanol (CAS 18173-64-3), with the linear formula (CH3)3CSi(CH3)2OH and a molecular weight of 132.28 g/mol, is an organosilicon compound. It functions as a valuable intermediate in organic synthesis, particularly in the formation of silyl ethers. Supplied by Tech Serve Solutions with an assay of 99%, it is suitable for research and development applications.
Organic Synthesis Intermediate
This silanol serves as a key building block in complex organic syntheses, enabling the introduction of the tert-butyldimethylsilyl (TBDMS) protecting group. Its reactivity is essential for protecting hydroxyl functionalities during multi-step reactions.
Silyl Ether Formation
tert-Butyldimethylsilanol is utilised for the efficient formation of silyl ethers from alcohols. This transformation is widely employed in the pharmaceutical and fine chemical industries to stabilise sensitive intermediates.
Research and Development
As a reagent with a defined purity of 99%, it is appropriate for laboratory-scale investigations and the development of novel synthetic methodologies.
| Molecular weight | 132.28 |
|---|---|
| Linear formula | (CH3)3CSi(CH3)2OH |
| Assay | 99% |
| Boiling point | 139 °C/739 mmHg(lit.) |
| Density | 0.84 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.424(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 1987C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is tert-Butyldimethylsilanol used for?
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tert-Butyldimethylsilanol is primarily used as an intermediate in organic synthesis, particularly for forming tert-butyldimethylsilyl ethers, which act as protecting groups for alcohols in multi-step chemical processes.
What is the CAS number and formula for tert-Butyldimethylsilanol?
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The CAS number is 18173-64-3 and the linear formula is (CH3)3CSi(CH3)2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies tert-Butyldimethylsilanol with an assay of 99%. This product is supplied for research and general laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should tert-Butyldimethylsilanol be handled safely?
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tert-Butyldimethylsilanol is a flammable liquid and vapour (H226), and can cause skin (H315), serious eye (H319), and respiratory tract irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area. Avoid heat, sparks, and open flames.
Is tert-Butyldimethylsilanol a controlled substance?
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Based on the provided data, tert-Butyldimethylsilanol is not indicated as a controlled or scheduled substance.
How is tert-Butyldimethylsilanol packed and shipped?
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tert-Butyldimethylsilanol is classified under UN 1987, Class 3, Packing Group III. It is exported in compliance with international shipping regulations for flammable liquids.
How can I request a sample or quote for tert-Butyldimethylsilanol?
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To request a sample or a quotation for tert-Butyldimethylsilanol, please contact our sales department through the website or by phone, providing your specific requirements.
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