Nystatin

CAS 1400-61-9Biochemicals & Reagents

Nystatin (CAS: 1400-61-9) is a polyene antibiotic recognised for its antifungal properties. This premium quality reagent is supplied in a sterile, gamma-irradiated form and is suitable for cell culture applications. It is particularly noted for its ability to prevent cell culture contamination and its role in inducing cytokine secretion in specific cell lines, making it a valuable tool in biological research laboratories.

IUPAC: Fungicidin,Mycostatin
Synonyms: FungicidinMycostatin

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Nystatin — chemical structure, CAS 1400-61-9; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics N-SAntifungalBiochemicals and ReagentsChemical Structure ClassMechanism of ActionPolyenesSpectrum of Activity More...

01 /Applications

Cell Culture Contamination Prevention

Nystatin is utilised in cell culture media to prevent contamination by fungi, ensuring the integrity and reliability of experimental results. Its efficacy against a broad spectrum of yeasts and fungi makes it a standard component in many cell culture protocols.

Immunomodulation Research

This compound is employed in research settings to study immune responses. It is known to induce the secretion of key cytokines such as IL-1, IL-8, and TNF-α in TLR2-expressing THP1 cells, facilitating investigations into innate immunity pathways.

Biochemical Research Reagent

As a PREMIUM grade biochemical, Nystatin serves as a versatile reagent for various laboratory investigations. Its specific mechanism of action, interfering with cell membrane permeability, makes it useful for studying cellular processes.

02 /Properties

Solubility	H2O: insoluble
Concentration	10,000 unit/mL in DPBS
Storage temperature	−20°C
Impurities tested	endotoxin, tested
Application	Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells†. This product is recommended for use in cell culture applications at 50 mg/L.
Suitability	suitable for cell culture

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1400-61-9

MDL number

MFCD25541651

PubChem substance

24897647

05 /Additional specifications

Quality Level	PREMIUM
Sterility	γ-irradiated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Nystatin used for?

Nystatin is primarily used to prevent fungal contamination in cell cultures and in research studies to investigate its effects on cell membrane permeability and its ability to induce cytokine secretion.

What is the CAS number and formula for Nystatin?

The CAS number for Nystatin is 1400-61-9. The chemical formula is not provided in the product data.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Nystatin at a PREMIUM quality level, tested for endotoxins and sterility (gamma-irradiated). The specific assay is not detailed beyond suitability for cell culture and research applications. TSS does not represent this product as USP, BP, or EP grade.

How should Nystatin be handled and stored?

Handling requires personal protective equipment including eyeshields and gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store Nystatin at -20°C. Water solubility is listed as insoluble.

Is Nystatin a controlled substance?

The provided data does not indicate that Nystatin is a controlled substance.

How can I order Nystatin or request a quote?

To request a quote or place an order for Nystatin, please contact the TSS sales department via our website or by telephone. We also offer sample requests for qualified researchers.

How is Nystatin shipped?

Nystatin is supplied sterile, gamma-irradiated, and is intended for research use. Shipping and export procedures adhere to all relevant regulations for chemical reagents.