Boc-β-iodo-D-Ala-OBzl

CAS 125942-79-2ICH2CH[NHCO2C(CH3)3]CO2CH2C6H5Chemical Synthesis

N-(tert-Butoxycarbonyl)-3-iodo-D-alanine benzyl ester (CAS: 125942-79-2) is a protected unnatural amino acid derivative used in chemical synthesis and peptide chemistry. With a molecular weight of 405.23 g/mol, this compound serves as a valuable building block in the creation of complex molecules. Its structure incorporates a Boc protecting group and an iodide functionality, enabling specific synthetic transformations.

IUPAC: N-(tert-Butoxycarbonyl)-3-iodo-D-alanine benzyl ester,Boc-3-iodo-D-alanine benzyl ester
Synonyms: N-(tert-Butoxycarbonyl)-3-iodo-D-alanine benzyl esterBoc-3-iodo-D-alanine benzyl ester

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Boc-β-iodo-D-Ala-OBzl (ICH2CH[NHCO2C(CH3)3]CO2CH2C6H5) — chemical structure, CAS 125942-79-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Alanine DerivativesChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

This unnatural amino acid derivative is employed in solid-phase and solution-phase peptide synthesis. It allows for the incorporation of modified alanine residues into peptide chains, facilitating the study of peptide structure-activity relationships or the development of novel peptidomimetics.

Chemical Biology Research

As a specialized building block, it is used in chemical biology to construct probes or modified biomolecules. The iodide substituent can be further functionalized, making it useful for labeling studies or creating molecules with unique biological activities.

Organic Synthesis

The compound serves as a versatile intermediate in general organic synthesis. The presence of both the Boc-protected amine and the benzyl ester, along with the reactive iodide, provides multiple points for chemical modification and elaboration into more complex targets.

02 /Properties

Molecular weight	405.23
Linear formula	ICH2CH[NHCO2C(CH3)3]CO2CH2C6H5
Assay	≥98.0% (TLC)
Optical activity	[α]20/D +18±1°, c = 1% in ethanol
Storage temperature	2-8°C
Melting point	80-84 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

125942-79-2

MDL number

MFCD00191867

Beilstein registry

5854502

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-β-iodo-D-Ala-OBzl used for?

Boc-β-iodo-D-Ala-OBzl is primarily used as a building block in peptide synthesis, chemical biology research, and general organic synthesis due to its unnatural amino acid structure with a Boc protecting group and an iodide functionality.

What is the CAS number and formula for Boc-β-iodo-D-Ala-OBzl?

The CAS number is 125942-79-2. The linear formula is ICH₂CH[NHCO₂C(CH₃)₃]CO₂CH₂C₆H₅.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-β-iodo-D-Ala-OBzl with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

What are the safety and handling recommendations for this chemical?

This compound requires the use of Eyeshields, Gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is classified with WGK 3 in Germany, indicating a high hazard to water.

How is Boc-β-iodo-D-Ala-OBzl shipped and exported?

Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, including Boc-β-iodo-D-Ala-OBzl, adhering to all relevant shipping and export regulations.