Novobiocin sodium
Novobiocin sodium (CAS 1476-53-5), a coumarin-glycoside antibiotic with the formula C31H35N2NaO11 and a molecular weight of 634.61 g/mol, is supplied by TSS. This compound functions as an inhibitor of bacterial DNA gyrase, eukaryotic DNA topoisomerase, and retrovirus RNA-dependent DNA-polymerase. It is also used for the production of positively supercoiled plasmid DNA, making it valuable in molecular biology and research applications.
- IUPAC
- Novobiocin sodium salt
DNA Supercoiling Production
Novobiocin sodium is utilised in the laboratory for the production of positively supercoiled plasmid DNA. This application is crucial for various molecular biology techniques and research.
Enzyme Inhibition
It acts as an inhibitor for bacterial DNA gyrase and eukaryotic DNA topoisomerase. Additionally, it inhibits retrovirus RNA-dependent DNA-polymerase, supporting its use in biochemical research.
Antibacterial Research
As an antibiotic, Novobiocin sodium can be employed in research settings to study bacterial growth inhibition and mechanisms of action. Its properties are relevant for microbiological investigations.
| Molecular weight | 634.61 |
|---|---|
| Empirical formula | C31H35N2NaO11 |
| Assay | ≥90% (HPLC) |
| Storage temperature | 2-8°C |
| Application | For the production of positively supercoiled plasmid DNA.1 Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase.2 Inhibitor of retrovirus RNA-dependent DNA-polymerase.3 |
| Suitability | meets USP testing specifications |
Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Novobiocin sodium used for?
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Novobiocin sodium is used for the production of positively supercoiled plasmid DNA. It also functions as an inhibitor of bacterial DNA gyrase, eukaryotic DNA topoisomerase, and retrovirus RNA-dependent DNA-polymerase.
What are the CAS number and formula for Novobiocin sodium?
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The CAS number for Novobiocin sodium is 1476-53-5, and its empirical formula is C31H35N2NaO11.
What grade and purity does Tech Serve Solutions supply?
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TSS supplies Novobiocin sodium with an assay of ≥90% by HPLC. It meets USP testing specifications. TSS does not represent this product as pharmacopoeia grade unless explicitly stated.
How should Novobiocin sodium be handled safely?
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Novobiocin sodium is a warning substance that may cause skin irritation and serious eye irritation (H317, H319). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves. Ensure good ventilation.
How is Novobiocin sodium packed, shipped, and exported?
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Novobiocin sodium is typically stored at 2-8°C. TSS professionally packs and exports fine chemicals globally, adhering to all necessary regulations for safe and compliant international shipping.
How can I request a quote or sample of Novobiocin sodium?
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To request a quote or a sample of Novobiocin sodium, please contact our sales team through the website or by phone, providing your specific requirements.
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