Boc-β-Leu-OH
Boc-β-Leu-OH (CAS 183990-64-9), with the empirical formula C11H21NO4 and a molecular weight of 231.29 g/mol, is a protected beta-amino acid derivative. It is a valuable building block in organic synthesis, particularly in the fields of peptide chemistry and chemical biology. This compound is often employed in the development of unnatural amino acid derivatives for novel peptide structures and pharmaceutical research.
- IUPAC
- (R)-3-(Boc-amino)-4-methylpentanoic acid,Boc-L-β-homovaline,Boc-L-β-leucine
- Synonyms
- (R)-3-(Boc-amino)-4-methylpentanoic acidBoc-L-β-homovalineBoc-L-β-leucine

Peptide Synthesis
Boc-β-Leu-OH serves as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with modified backbones and unique structural properties.
Chemical Biology Research
This compound is utilised in chemical biology for constructing peptides with enhanced stability, altered biological activity, or novel functionalities. It contributes to the study of protein structure-function relationships.
Drug Discovery and Development
As a specialised building block, Boc-β-Leu-OH finds application in medicinal chemistry programmes aimed at synthesising novel therapeutic agents. Its inclusion can modify pharmacokinetic or pharmacodynamic properties.
Organic Synthesis Intermediate
The compound is a versatile intermediate for various organic transformations, enabling the synthesis of complex molecules and research chemicals.
| Molecular weight | 231.29 |
|---|---|
| Empirical formula | C11H21NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-β-Leu-OH used for?
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Boc-β-Leu-OH is primarily used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, and drug discovery programmes for creating novel peptide structures and complex organic molecules.
What are the CAS number and formula for Boc-β-Leu-OH?
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The CAS number for Boc-β-Leu-OH is 183990-64-9, and its empirical formula is C11H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-β-Leu-OH with an assay of ≥98.0% (TLC). This is a research grade material, and TSS does not represent it as USP, BP, or EP.
What are the safety precautions for handling Boc-β-Leu-OH?
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Handling Boc-β-Leu-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is Boc-β-Leu-OH packed and shipped?
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Boc-β-Leu-OH is carefully packed and exported by Tech Serve Solutions, a global supplier, ensuring product integrity during transit.
How can I request a quote or sample for Boc-β-Leu-OH?
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To request a quote or sample of Boc-β-Leu-OH, please contact Tech Serve Solutions directly through our website or sales department.
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