Boc-β-Phe-OH

CAS 161024-80-2C14H19NO4Chemical Synthesis

Boc-β-Phe-OH (CAS: 161024-80-2), with the molecular formula C14H19NO4 and a molecular weight of 265.30, is an N-terminal protected beta-amino acid derivative. It is primarily utilised in solid-phase peptide synthesis (SPPS) for the incorporation of beta-phenylalanine residues into peptide chains. This compound serves as a valuable building block in the development of novel peptides and peptidomimetics for research applications.

IUPAC: (R)-3-(Boc-amino)-3-phenylpropionic acid,Boc-L-β-phenylalanine
Synonyms: (R)-3-(Boc-amino)-3-phenylpropionic acidBoc-L-β-phenylalanine

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Boc-β-Phe-OH (C14H19NO4) — chemical structure, CAS 161024-80-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino AcidsBeta-Amino AcidsBiochemicals and ReagentsChemical BiologyChemical SynthesisModified Amino AcidsPeptide Chemistry

01 /Applications

Peptide Synthesis

Boc-β-Phe-OH is a crucial reagent in solid-phase peptide synthesis (SPPS). It allows for the controlled introduction of the unnatural amino acid β-phenylalanine into peptide sequences, enabling the creation of modified peptides with unique structural and functional properties.

Chemical Biology Research

As a modified amino acid derivative, Boc-β-Phe-OH is employed in chemical biology to synthesise peptides or peptidomimetics. These molecules can be used to probe biological pathways, develop diagnostic tools, or as potential therapeutic agents.

Drug Discovery and Development

The incorporation of unnatural amino acids like β-phenylalanine can enhance the stability, bioavailability, or receptor binding affinity of peptide-based drug candidates. Boc-β-Phe-OH is therefore a key intermediate in the exploration of novel therapeutics.

02 /Properties

Molecular weight	265.30
Empirical formula	C14H19NO4
Assay	≥96.0% (HPLC)
Application	Boc-L-β-Phenylalanine is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make peptides containing β-phenylalanine residues.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

161024-80-2

MDL number

MFCD01320859

Beilstein registry

5404389

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-β-Phe-OH used for?

Boc-β-Phe-OH is an N-terminal protected beta-amino acid used in solid-phase peptide synthesis (SPPS) for creating peptides that contain beta-phenylalanine residues.

What is the CAS number and formula for Boc-β-Phe-OH?

The CAS number for Boc-β-Phe-OH is 161024-80-2, and its molecular formula is C14H19NO4.

What grade and purity does Tech Serve Solutions supply for Boc-β-Phe-OH?

Tech Serve Solutions supplies Boc-β-Phe-OH with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling requirements for Boc-β-Phe-OH?

Appropriate personal protective equipment, including eyeshields and gloves, should be worn when handling Boc-β-Phe-OH. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product is classified under WGK Germany 3.

How is Boc-β-Phe-OH packed, shipped, and exported by TSS?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to strict quality control and safe handling protocols for all shipments.