SM-19712 hydrate
SM-19712 hydrate (CAS: 194542-56-8), with the empirical formula C18H13ClN5NaO3S · xH2O, is an off-white to light brown powder. This compound is recognised for its role as an Endothelin converting enzyme (ECE) inhibitor. Research has explored its potential application in understanding and developing therapeutic strategies for conditions such as Alzheimer's disease, by examining the efficacy of ECE inhibition.
- IUPAC
- 4-Chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt hydrate
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Alzheimer's Disease Research
SM-19712 hydrate has been utilised in scientific studies to investigate the potential of Endothelin converting enzyme (ECE) inhibition as a therapeutic avenue for Alzheimer's disease. Research aims to determine the effectiveness of blocking ECE activity in managing disease progression.
Endothelin Converting Enzyme (ECE) Inhibition
As a specific inhibitor of ECE, SM-19712 hydrate serves as a crucial research tool for biochemical and pharmacological studies. It aids in elucidating the role of ECE in various physiological and pathological processes.
Biochemical and Cell Biology Studies
This compound is valuable in biochemical research and cell biology, particularly for studies involving enzyme pathways and cellular signalling. Its known inhibitory action on ECE makes it useful for probing biological mechanisms.
| Empirical formula | C18H13ClN5NaO3S · xH2O |
|---|---|
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white to light brown |
| Solubility | DMSO: ≥20 mg/mLH2O: ≥20 mg/mL |
| Storage temperature | 2-8°C |
| Application | SM-19712 hydrate was used in studies to determine the effectiveness of ECE inhibition as a treatment option for Alzheimer′s disease.1 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SM-19712 hydrate used for?
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SM-19712 hydrate is used in research to study Endothelin converting enzyme (ECE) inhibition, particularly its potential therapeutic implications for conditions like Alzheimer's disease.
What is the CAS number and chemical formula for SM-19712 hydrate?
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The CAS number for the anhydrous form is 194542-56-8. The empirical formula is C18H13ClN5NaO3S · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SM-19712 hydrate with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should SM-19712 hydrate be handled safely?
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SM-19712 hydrate is a warning substance that may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), wear eyeshields and gloves. Ensure good ventilation.
How is SM-19712 hydrate packed, shipped, and exported?
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SM-19712 hydrate is carefully packed for stability and safety. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a sample or a quote for SM-19712 hydrate?
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To request a sample or a quote, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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