SKF-86466 hydrochloride

CAS 86129-54-6C11H14ClN·HClBiochemicals & Reagents

SKF-86466 hydrochloride (CAS 86129-54-6), a chemical compound with the formula C11H14ClN·HCl and a molecular weight of 232.15 g/mol, presents as a white solid. This substance has been utilised in research to investigate adrenoceptor signalling pathways, particularly within rat limbic seizure models. Its properties make it a valuable tool for neuroscientific research and the study of related physiological processes.

IUPAC: 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine hydrochloride
Synonyms: 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine hydrochloride

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SKF-86466 hydrochloride (C11H14ClN·HCl) — chemical structure, CAS 86129-54-6; Life Science, fine chemical supplied by Tech Serve Solutions

AdrenergicsAdrenergics - AntagonistsAntagonistsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscience

01 /Applications

Adrenoceptor Signalling Research

SKF-86466 hydrochloride has been employed in studies focusing on the intricate mechanisms of adrenoceptor signalling. Its application in rat limbic seizure models provides insights into the role of these receptors in neurological processes.

Neuroscience Research Tool

As a specific modulator of adrenoceptor pathways, this compound serves as a valuable reagent for researchers in neuroscience. It aids in understanding neurotransmission and related cellular functions within the central nervous system.

GPCR Modulator Studies

This chemical falls under the category of GPCR modulators, making it relevant for studies investigating G protein-coupled receptors. Its use contributes to the broader understanding of cellular responses and signalling cascades involving these receptor types.

02 /Properties

Molecular weight	232.15
Linear formula	C11H14ClN·HCl
Assay	≥98% (HPLC)
Form	solid
Colour	white
Solubility	H2O: soluble24 mg/mL
Application	SKF 86466 was used to study adrenoceptor signaling in rat limbic seizure models.1,2

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

86129-54-6

MDL number

MFCD03453012

05 /Additional specifications

Gene Information	human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SKF-86466 hydrochloride primarily used for?

SKF-86466 hydrochloride is primarily used in research for studying adrenoceptor signalling pathways, particularly within models such as rat limbic seizure models.

What are the CAS number and chemical formula for SKF-86466 hydrochloride?

The CAS number for SKF-86466 hydrochloride is 86129-54-6, and its chemical formula is C11H14ClN·HCl.

What grade and purity does Tech Serve Solutions supply for SKF-86466 hydrochloride?

Tech Serve Solutions supplies SKF-86466 hydrochloride with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety considerations when handling SKF-86466 hydrochloride?

When handling SKF-86466 hydrochloride, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The product is classified under WGK Germany 3.

How is SKF-86466 hydrochloride typically packed and shipped?

SKF-86466 hydrochloride is supplied as a white solid. TSS can export this chemical globally, adhering to all relevant shipping regulations.

How can I request a sample or a quote for SKF-86466 hydrochloride?

To request a sample or a quote for SKF-86466 hydrochloride, please contact our sales team through the website or by phone. We will respond promptly to your inquiry.