SKF-83959 hydrobromide
SKF-83959 hydrobromide (CAS: 80751-85-5) is a research chemical supplied by TSS. This tetrahydro-1H-3-benzazepine derivative presents as a white solid with a molecular weight of 398.72 g/mol and empirical formula C18H20NClO2 · HBr. Primarily utilised in neuroscience research, it serves as a tool for investigating dopamine signaling pathways, G-protein coupled receptors, and related cellular mechanisms. Its defined properties make it valuable for in vitro and in vivo studies.
- IUPAC
- 6-Chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- Synonyms
- 6-Chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
Dopamine Signaling Studies
SKF-83959 hydrobromide has been employed in research investigating dopamine signaling pathways. Studies have utilised this compound to explore its effects on biological processes such as eye blinking in primate models.
Protein Phosphorylation Research
This chemical has been used as a tool in studies examining protein phosphorylation, specifically in the context of CaMKIIα phosphorylation in mouse models, contributing to the understanding of cellular signaling cascades.
Neuroscience and Cell Biology Research
As a bioactive small molecule, SKF-83959 hydrobromide is instrumental in cellular signaling and neuroscience research, aiding investigations into neurotransmission and neuronal function.
| Molecular weight | 398.72 |
|---|---|
| Empirical formula | C18H20NClO2 · HBr |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mLH2O: insoluble |
| Application | SKF-83959 was used in dopamine signaling studies on eye blinking in monkeys1 and on phosphorylation of CaMKIIα in mice.2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SKF-83959 hydrobromide used for?
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SKF-83959 hydrobromide is primarily used as a research chemical in neuroscience, cell biology, and cell signaling studies, particularly for investigating dopamine pathways and protein phosphorylation.
What is the CAS number and formula for SKF-83959 hydrobromide?
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The CAS number for SKF-83959 hydrobromide is 80751-85-5, and its empirical formula is C18H20NClO2 · HBr.
What grade and purity does Tech Serve Solutions supply for SKF-83959 hydrobromide?
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Tech Serve Solutions supplies SKF-83959 hydrobromide with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling SKF-83959 hydrobromide?
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When handling SKF-83959 hydrobromide, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3.
How is SKF-83959 hydrobromide shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including SKF-83959 hydrobromide, ensuring compliant packaging and shipping for international destinations.
How can I request a sample or quote for SKF-83959 hydrobromide?
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To request a sample or a quote for SKF-83959 hydrobromide, please contact our sales department through the TSS website or by phone.
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