(S)-(−)-Propranolol hydrochloride

CAS 4199-10-4C10H7OCH2CH(OH)CH2NHCH(CH3)2·HClBiochemicals & Reagents

(S)-(−)-Propranolol hydrochloride (CAS: 4199-10-4) is a beta-adrenergic receptor antagonist. It is supplied by TSS as a powder with a purity of ≥98% (TLC). This compound is recognised for its role in modulating adrenergic signalling pathways and is widely utilised in research settings for investigating cardiovascular and neurological functions. Its specific stereochemistry is crucial for its biological activity, making it a valuable tool for pharmacological studies.

IUPAC: (S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride

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(S)-(−)-Propranolol hydrochloride (C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl) — chemical structure, CAS 4199-10-4; Life Science, fine chemical supplied by Tech Serve Solutions

AdrenergicsAdrenergics - AntagonistsAntagonistsAstraZenecaBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and Antibodies

01 /Applications

Pharmacological Research

Utilised as a research chemical to study beta-adrenergic receptor antagonism and its effects on physiological systems. It serves as a standard for in vitro and in vivo experiments investigating cardiovascular and neurological processes.

Drug Discovery and Development

Acts as a reference compound in the development of new therapeutic agents targeting adrenergic pathways. Its known activity profile aids in the screening and evaluation of novel drug candidates.

Biochemical Studies

Employed in biochemical assays to investigate receptor binding affinities and signal transduction mechanisms. Its well-defined structure and activity make it suitable for detailed mechanistic studies.

02 /Properties

Molecular weight	295.80
Linear formula	C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl
Assay	≥98% (TLC)
Form	powder
Solubility	ethanol: soluble10 mg/mLDMSO: H2O: soluble50 mg/mL (With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble8.0 mg/mL
Optical activity	[α]25/D −25.5°, c = 1.0 in ethanol(lit.)
Storage temperature	2-8°C
Melting point	193-195 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22
Safety statements (S)	36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

4199-10-4

MDL number

MFCD00064547

PubChem substance

24278657

Beilstein registry

3574966

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-Propranolol hydrochloride used for?

(S)-(−)-Propranolol hydrochloride is primarily used in pharmacological and biochemical research as a selective beta-adrenergic receptor antagonist to study its effects on physiological systems and as a reference compound in drug discovery.

What is the CAS number and formula for (S)-(−)-Propranolol hydrochloride?

The CAS number is 4199-10-4, and the linear formula is C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-(−)-Propranolol hydrochloride with a purity of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for this chemical?

This compound is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area.

Is (S)-(−)-Propranolol hydrochloride a controlled substance?

The provided data does not indicate that (S)-(−)-Propranolol hydrochloride is a controlled substance.

How is (S)-(−)-Propranolol hydrochloride packed and shipped?

Products are typically packed in suitable containers for chemical transport and are exported globally by TSS, adhering to all relevant shipping regulations.

How can I request a quote or sample?

To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (4199-10-4).