(S)-(+)-4-(3-Amino-pyrrolidino)-7-nitrobenzofurazan
(S)-(+)-4-(3-Amino-pyrrolidino)-7-nitrobenzofurazan (CAS: 143112-52-1) is a benzofurazan derivative with the molecular formula C10H11N5O3 and a molecular weight of 249.23 g/mol. This compound is particularly noted for its fluorescence properties. It is suitable for fluorescence applications and is often employed as a derivatization reagent, particularly in high-performance liquid chromatography (HPLC), to enhance detection sensitivity.
- IUPAC
- (S)-(+)-NBD-Apy,(S)-(+)-1-(7-Nitro-4-benzofurazanyl)-3-pyrrolidinamine
- Synonyms
- (S)-(+)-NBD-Apy(S)-(+)-1-(7-Nitro-4-benzofurazanyl)-3-pyrrolidinamine
Fluorescence Derivatization Agent
(S)-(+)-4-(3-Amino-pyrrolidino)-7-nitrobenzofurazan serves as an effective derivatization agent for enhancing fluorescence detection. Its ability to react with target analytes allows for improved sensitivity in analytical techniques such as HPLC, facilitating the detection of compounds that might otherwise be difficult to observe.
Analytical Chemistry Reagent
As an analytical reagent, this compound is valuable in chromatographic methods. Its specific optical properties, including excitation and emission wavelengths, make it suitable for a range of analytical procedures where fluorescence is a key detection mechanism.
Biochemical and Membrane Research
This benzofurazan derivative is classified under biochemicals and reagents, and its fluorescent properties make it useful in studies involving membrane research. It can function as a lipophilic probe or stain, aiding in the visualisation and study of cellular structures and processes.
| Molecular weight | 249.23 |
|---|---|
| Empirical formula | C10H11N5O3 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D +13.6±2° |
| Storage temperature | 2-8°C |
| Suitability | suitable for fluorescence |
| Melting point | 178-184 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex ≥490 nm; λem ≥535 nm in acetonitrile |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-4-(3-Amino-pyrrolidino)-7-nitrobenzofurazan used for?
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This compound is primarily used as a fluorescence derivatization agent in analytical chemistry, particularly for HPLC, and in biochemical research, including membrane studies.
What is the CAS number and molecular formula?
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The CAS number is 143112-52-1, and the molecular formula is C10H11N5O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling precautions?
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This compound is classified with GHS07 and a Warning signal word. It is associated with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is this chemical supplied and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(+)-4-(3-Amino-pyrrolidino)-7-nitrobenzofurazan. It is stored at 2-8°C and shipped according to relevant regulations.
How can I request a sample or quote?
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To request a sample or a quote for (S)-(+)-4-(3-Amino-pyrrolidino)-7-nitrobenzofurazan, please contact our sales department through our website or by phone.
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