(S)-(+)-Clopidogrel hydrogensulfate
(S)-(+)-Clopidogrel hydrogensulfate (CAS: 120202-66-6) is a high-purity white to tan powder, with a molecular weight of 419.90 g/mol and an empirical formula of C16H16ClNO2S · H2SO4. This compound, assaying ≥98% by HPLC, serves as a crucial reference standard in analytical chemistry, particularly for the detection and quantification of clopidogrel and its metabolites in biological samples. Its primary application lies in pharmaceutical research and development, supporting the study of anticoagulation mechanisms.
- IUPAC
- (S)-(+)-Clopidogrel bisulfate,(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate,Clopidogrel Bisulphate
- Synonyms
- (S)-(+)-Clopidogrel bisulfate(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfateClopidogrel Bisulphate
Analytical Reference Standard
(S)-(+)-Clopidogrel hydrogensulfate is utilized as a certified reference material in High-Performance Liquid Chromatography coupled with Tandem Mass Spectrometry (HPLC-MS/MS). It aids in the precise identification and quantification of clopidogrel and its thiol derivative in human plasma, ensuring accuracy in pharmacokinetic and pharmacodynamic studies.
Pharmaceutical Research
This compound is integral to research focused on antiplatelet aggregation mechanisms and the development of novel anticoagulant therapies. Its role as a standard supports the validation of analytical methods for drug discovery and quality control within the pharmaceutical industry.
Biochemical Studies
As a P2 Nucleotide Receptor antagonist, it facilitates research into purinergic signaling pathways. This is particularly relevant in cell biology and neuroscience, where understanding these receptors' roles in various physiological and pathological processes is critical.
| Molecular weight | 419.90 |
|---|---|
| Empirical formula | C16H16ClNO2S · H2SO4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥20 mg/mL (warmed) |
| Optical activity | [α]/D +54 to +70°, c = 0.5 in methanol |
| Storage temperature | 2-8°C |
| Application | (S)-(+)-Clopidogrel hydrogensulfate was used as standard in HPLC-MS/MS to detect clopidogrel and its thiol derivative in human plasma.1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Clopidogrel hydrogensulfate used for?
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(S)-(+)-Clopidogrel hydrogensulfate is primarily used as an analytical reference standard in HPLC-MS/MS for detecting clopidogrel and its metabolites in biological matrices like human plasma. It also serves as a tool in pharmaceutical research related to anticoagulation and purinergic signaling.
What is the CAS number and molecular formula for (S)-(+)-Clopidogrel hydrogensulfate?
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The CAS number for (S)-(+)-Clopidogrel hydrogensulfate is 120202-66-6. Its empirical formula in Hill notation is C16H16ClNO2S · H2SO4, and its molecular weight is 419.90 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-Clopidogrel hydrogensulfate with an assay of ≥98% determined by HPLC. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for (S)-(+)-Clopidogrel hydrogensulfate?
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(S)-(+)-Clopidogrel hydrogensulfate is classified with a WGK (German Water Hazard Class) of 3, indicating a high hazard to water. Handle with appropriate personal protective equipment in a well-ventilated area to avoid inhalation, ingestion, and skin contact.
How is (S)-(+)-Clopidogrel hydrogensulfate packed, shipped, and exported?
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This compound is typically supplied as a white to tan powder. Shipping and export are handled in compliance with all relevant national and international regulations for chemical substances.
How can I request a sample or a quote for (S)-(+)-Clopidogrel hydrogensulfate?
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To request a sample or obtain a quotation, please contact the Tech Serve Solutions sales team through our website or direct contact details, specifying the product name and CAS number.
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