(S)-(+)-Camptothecin

CAS 7689-03-4C20H16N2O4Biochemicals & Reagents

(S)-(+)-Camptothecin (CAS: 7689-03-4), with the molecular formula C20H16N2O4 and a molecular weight of 348.35, is a naturally occurring pentacyclic alkaloid. It is known for its potent antineoplastic and antitumor properties, acting as a topoisomerase I inhibitor. This compound is primarily utilized in cancer research and as a building block for developing novel anticancer therapeutics. Tech Serve Solutions supplies this chemical in powder form with a guaranteed purity of ≥90% by HPLC.

Email us

(S)-(+)-Camptothecin (C20H16N2O4) — chemical structure, CAS 7689-03-4; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics A-FAntibiotics by ApplicationAntitumor AgentsApoptosis and Cell CycleBioactive Small MoleculesBiochemicals and ReagentsC-CHCancer Research

01 /Applications

Anticancer Research

Utilized as a key reference compound and research tool in the study of topoisomerase I inhibition and its effects on cancer cells. Its mechanism involves stabilizing the DNA-topoisomerase I covalent complex, leading to DNA damage and apoptosis.

Drug Discovery and Development

Serves as a crucial starting material or intermediate for the synthesis of camptothecin analogues and derivatives with improved efficacy, reduced toxicity, and better pharmacokinetic profiles for cancer chemotherapy.

Cell Biology Studies

Investigated for its role in cell cycle arrest and apoptosis, providing insights into fundamental cellular processes relevant to cancer biology and drug development.

02 /Properties

Molecular weight	348.35
Empirical formula	C20H16N2O4
Assay	≥90% (HPLC)
Form	powder
Solubility	chloroform/methanol (4:1): soluble5 mg/mL
Storage temperature	2-8°C
Melting point	260 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 1544 6.1/PG 3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

7689-03-4

MDL number

MFCD00081076

PubChem substance

24278352

Beilstein registry

631069

05 /Additional specifications

Gene Information	human ... TOP1(7150)mouse ... Prkca(18750)rat ... Sstr2(54305)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (S)-(+)-Camptothecin used for?

(S)-(+)-Camptothecin is used in cancer research, particularly for studying topoisomerase I inhibition, and as a precursor in the development of anticancer drugs.

What are the CAS number and molecular formula for (S)-(+)-Camptothecin?

The CAS number is 7689-03-4 and the molecular formula is C20H16N2O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-(+)-Camptothecin with an assay of ≥90% by HPLC. This is a research-grade material, and TSS does not represent it as USP, BP, or EP.

How should (S)-(+)-Camptothecin be handled and stored?

Handle with appropriate personal protective equipment including eyeshields, face shields, and gloves. Use a P2 (EN 143) respirator if necessary. Store at 2-8°C.

Is (S)-(+)-Camptothecin a controlled substance?

According to the provided data, (S)-(+)-Camptothecin is classified under UN 1544, Hazard Class 6.1, Packing Group III (Toxic substances). Specific controlled substance status may vary by jurisdiction.

How is this product shipped?

This product is shipped as a UN 1544, Class 6.1, Packing Group III hazardous material, requiring specific packaging and handling procedures for export.